The Virginia Cavaliers will look to make it six straight wins when they visit Bill Belichick and the North Carolina Tar Heels on Saturday afternoon.
UNC found a way to win last week, but it's severely outmatched in this game, which is why I’m taking the Cavaliers to cover in my Virginia vs. North Carolina predictions.
Keep reading for a full breakdown of this ACC matchup in my free college football picks for Saturday, October 25.
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Virginia vs North Carolina prediction
Virginia vs North Carolina best bet: Virginia -10.5 (-110)
North Carolina has been one of the biggest stories in college football this season, but for all the wrong reasons. Belichick’s foray into college football has gone horribly wrong so far, as the Tar Heels sit at 2-4 and have yet to score a win against a power conference opponent.
Things only get harder this week as the Tar Heels face their first-ranked opponent in Virginia, which enters this game riding a five-game winning streak. While the Cavaliers have played a couple of close games in recent weeks, they’ve been outstanding offensively, averaging an impressive 40.0 ppg on the season.
That presents two issues for the Tar Heels. First, North Carolina is unlikely to keep up with that kind of offensive firepower, as it's averaging just 12.8 ppg against power-conference opponents.
Secondly, the Tar Heels have given up 240.8 yards per game through the air while letting opponents complete 67.3% of their passes, giving the Cavs a clear avenue of attack in this game.
Quarterback Chandler Morris and the Virginia offense should shred the UNC defense, putting this game away early.
Virginia vs North Carolina same-game parlay
The Tar Heels have consistently played a low-scoring brand of football, to the point the Under is the better play even against an explosive Virginia offense.
But the Cavaliers will find success against a dreadful North Carolina secondary, with Harris being a solid pick to hit his modest yardage total as a result.
Virginia vs North Carolina SGP
- Virginia -10.5
- Under 51.5
- Trell Harris Over 43.5 receiving yards
Our deep-ball SGP: Feeling Trell
Since we’re already betting on a strong performance out of Harris, it makes sense to tack on a bet for the wide receiver to score a touchdown for added value on our parlay.
Virginia vs North Carolina SGP
- Virginia -10.5
- Under 51.5
- Trell Harris Over 43.5 receiving yards
- Trell Harris anytime touchdown
Virginia vs North Carolina odds
- Spread: Virginia -10.5 | North Carolina +10.5
- Moneyline: Virginia -405 | North Carolina +320
- Over/Under: Over 51.5 (-105) | Under 51.5 (-115)
Virginia vs North Carolina trend to know
[Stat]. Find more college football betting trends for Virginia vs North Carolina.
How to watch Virginia vs North Carolina
Location | Kenan Stadium, Chapel Hill, NC |
Date | Saturday, October 25, 2025 |
Kickoff | 12:00 p.m. ET |
TV | ACCN |
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Odds are correct at the time of publishing and are subject to change.
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