The Oklahoma State Cowboys travel to Chicago to face the 5-1 Northwestern Wildcats as part of a Thanksgiving night doubleheader.
My Oklahoma State vs. Northwestern predictions expect plenty of points in tonight's tilt.
Find out why in my free college basketball picks for Thursday, November 27.
Oklahoma State vs Northwestern prediction
Oklahoma State vs Northwestern best bet: Over 160 (-110)
The Northwestern Wildcats are 5-1 and are fresh off a 79-77 win against South Carolina, which was the fourth straight game they cashed the Over. The Wildcats are 11th in the country in 3-point percentage (41.9%) while turning the ball over at the 14th-lowest rate.
Now they face the Oklahoma State Cowboys, who are 6-0 to begin the year. The Cowboys are 16th in the country in points per game (93.2) and rank 38th in field goal percentage (49.7%)
The Pokes are deep with five players averaging double-digit points and 12 players logging more than 10 minutes per game. Vyctorius Miller (17.5 ppg on 58/50/88 shooting splits) and Jaylen Curry (15.5 ppg, 5.5 apg) have been the best of the bunch.
NU is led by Nick Martinelli, who is averaging 19.3 ppg with transfers Arrinten Page (15.7 points and 7.0 rebounds per game) and Jayden Reid (13.5 ppg, 6.2 apg) making a big impact as well.
The Wildcats are 59th in the country in average offensive possession length but rank dead last among 365 schools in opponent possession length.
They like to push the pace when they have the ball, but four of their six opponents (Mercyhurst, Boston University, Virginia, and South Carolina) are among the slowest teams in the country.
Going up against an OK State squad that ranks third in the country in adjusted tempo will lead to plenty of possessions for both sides. With both teams also shooting extremely well, expect this game to eclipse the lofty total.
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Oklahoma State vs Northwestern same-game parlay
While this game will take place at a neutral site, it'll feel like a home game for the Wildcats, who have to travel less than an hour to get here. The travel advantage and the familiarity of the venue should give them an edge against the Pokes, who have yet to play away from home this season.
Reid is just 5-foot-10 and has logged more than 2.5 boards just once in six games this season. The diminutive point guard will struggle on the glass against an OSU squad that is 32nd in the country in rebound rate.
Oklahoma State vs Northwestern SGP
- Over 160
- Northwestern -3.5
- Jayden Reid Under 2.5 rebounds
Our beyond the arc SGP: Sharpshooter
Nick Martinelli was a preseason All-Conference selection after leading the Big Ten in scoring last year. He's improved his perimeter shooting and is knocking down 1.5 threes per game at a 75% clip.
Oklahoma State vs Northwestern SGP
- Over 160
- Northwestern -3.5
- Jayden Reid Under 2.5 rebounds
- Nick Martinelli Over 1.5 threes
Oklahoma State vs Northwestern odds
- Spread: Oklahoma State +150 | Northwestern -180
- Moneyline: Oklahoma State +3.5 | Northwestern -3.5
- Over/Under: Over 160 | Under 160
Oklahoma State vs Northwestern betting trend to know
The Wildcats have cashed the Over in 23 of their last 33 games (+11.80 Units / 32% ROI). Find more college basketball betting trends for Oklahoma State vs. Northwestern.
How to watch Oklahoma State vs Northwestern
| Location | United Center, Chicago, IL |
| Date | Thursday, November 27, 2025 |
| Tip-off | 10:30 p.m. ET |
| TV | Big Ten Network |
Oklahoma State vs Northwestern key injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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