The stage is set for a potential NBA Finals preview as a pair of No. 2 seeds square off at Frost Bank Center tonight.
My Celtics vs. Spurs predictions put faith in the dynamic duo of Jayson Tatum and Jaylen Brown in a game that should be epic.
Here are my free NBA picks for this premier matchup on Tuesday, March 10.
Celtics vs Spurs prediction
Celtics vs Spurs best bet: Celtics moneyline (+125)
The Boston Celtics are 22-11 straight up on the road, winning five of their last six outside Boston.
A major part of that success was their Top 5 defensive rating, which held the Cavaliers' No. 4-ranked offense to 98 points in Cleveland.
A one-bucket spread shows oddsmakers expect a close game, and in close games, it's hard not to trust Jaylen Brown and Jayson Tatum over the San Antonio Spurs' young stars.
This defense will flex its muscles once more to remain undefeated since Tatum returned.
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Celtics vs Spurs same-game parlay
These are two of the best defenses in the Association, and the C's have been even more effective on the road, boasting a 110.6 defensive rating. Tonight's matchup will be a hard-fought, defensive battle.
Jayson Tatum posted 34 and 25 PRA in his first two games of the season, miraculously returning to the court ahead of schedule without much rust.
He doesn't need to score a ton of points to hit the Over on this line, as he went for 15/12/7 in his season debut.
Celtics vs Spurs SGP
- Celtics moneyline
- Under 222.5
- Jayson Tatum Over 31.5 points+rebounds+assists
Our "from downtown" SGP: Dynamic duo
Jaylen Brown's career-best 28.7 points per game have been a huge part of Boston's success this season, and the return of Tatum won't knock Brown's scoring average down significantly.
The 2024 NBA Finals MVP has scored 25+ in 41 of 57 appearances, and I expect him to step up against a formidable opponent in prime time.
Celtics vs Spurs SGP
- Celtics moneyline
- Under 222.5
- Jayson Tatum Over 31.5 points+rebounds+assists
- Jaylen Brown Over 24.5 points
Celtics vs Spurs odds
- Spread: Celtics +3.5 | Spurs -3.5
- Moneyline: Celtics -150 | Spurs +125
- Over/Under: Over 222.5 | Under 222.5
Celtics vs Spurs betting trend to know
The Boston Celtics have hit the game total Under in 30 of their last 40 games (+19.00 Units / 43% ROI). Find more NBA betting trends for Celtics vs. Spurs.
How to watch Celtics vs Spurs
| Location | Frost Bank Center, San Antonio, TX |
| Date | Tuesday, March 10, 2026 |
| Tip-off | 8:00 p.m. ET |
| TV | NBC |
Celtics vs Spurs latest injuries
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