The Philadelphia 76ers are going through their roughest stretch of the season, losing four straight games, all by double digits. Minnesota, meanwhile, has won three straight and seven of the last 10.
With key players missing for both sides, my 76ers vs. Timberwolves predictions and NBA picks look for Minnesota to get a home cover on Sunday, February 22.
76ers vs Timberwolves prediction
76ers vs Timberwolves best bet: Timberwolves -8.5 (-115)
Not only have the Philadelphia 76ers lost four straight by an average of 22.8 points, but three of them have also come against teams with a losing record. Coach Nick Nurse admitted the team has hit its toughest point this season.
The Minnesota Timberwolves should have their full attention on the Sixers. After winning two straight by more than 20, the T-Wolves jumped out to an 18-point lead against Dallas on Friday, only to play with their food a bit and allow the Mavericks to tie it late. All-Star MVP Anthony Edwards had 40 against Dallas and will continue his hot play in Philly.
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76ers vs Timberwolves same-game parlay
Edwards had 40 against Dallas and will be the focus of the Minnesota offense again today. He’s made more than half his shots and more than a third of his three-point attempts each of the last three games, with an All-Star MVP performance sandwiched in the middle.
With Gobert out, Julius Randle will need to help pick up the slack on the boards. Even with Gobert next to him, he’s had seven or more rebounds in four of the last five contests.
76ers vs Timberwolves SGP
- Timberwolves -8.5
- Edwards Over 29.5 points
- Julius Randle Over 7.5 rebounds
Our "from downtown" SGP: Edwards dials it up
The odds seem unusually long for Edwards’ three-pointers. He’s made four or more in four of the last five and hit five treys twice over that span. He’s 13 for his last 30 from three.
Like Randle, Naz Reid will need to pitch in more than usual to help with rebounding with Gobert out.
76ers vs Timberwolves SGP
- Edwards Over 29.5 points
- Julius Randle Over 7.5 rebounds
- Reid Over 8.5 rebounds
- Edwards Over 3.5 threes
76ers vs Timberwolves odds
- Spread: 76ers +8.5 | Timberwolves -8.5
- Moneyline: 76ers +290 | Timberwolves -370
- Over/Under: Over 238.5 | Under 238.5
76ers vs Timberwolves betting trend to know
The Minnesota Timberwolves have hit the Game Total Under in 18 of their last 25 games at home. Find more NBA betting trends for 76ers vs. Timberwolves.
How to watch 76ers vs Timberwolves
| Location | Target Center, Minneapolis, MN |
| Date | Sunday, February 22, 2026 |
| Tip-off | 7:00 p.m. ET |
| TV | NBC Sports Philadelphia, FDSN North |
76ers vs Timberwolves latest injuries
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