Cubs vs White Sox Prediction, Picks & Odds — Sunday, July 27

With Ben Brown and Grant Taylor kicking things off on the mound, our Cubs vs. White Sox predictions expect runs to come from both sides.

Todd Cordell - Betting Analyst at Covers.com
Todd Cordell • Betting Analyst
Jul 27, 2025 • 11:00 ET • 4 min read

MLB

Match starts: 17 mins
CHW
42 %
CHC
58 %
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Pete Crow-Armstrong Chicago Cubs MLB
Photo By - Imagn Images. Pete Crow-Armstrong celebrates in the dugout.

The start of this series has featured plenty of fireworks, with 24 runs being scored through two games.

My Cubs vs White Sox predictions see the offenses winning out once again in what should be an exciting finale. Let’s take a closer look with my July 27 MLB picks.

Cubs vs White Sox prediction

My Cubs vs White Sox best bet: Over 8.5 (-105 at Caesars)

The Chicago Cubs are one of the best offensive teams in the majors. They sit tied for first in runs per game, second in hits, and third in homers. They hit for average, they hit for power, and they are nearly impossible to slow down due to all the firepower in their lineup.

The Chicago White Sox are expected to go with Grant Taylor to start things off. While a very highly touted prospect, he’s pitched just 18 1/3 innings in his Big League career. Slowing down the Cubs out of the gate is a tough challeng

Backing him up will be an exploitable bullpen that ranks 29th in xFIP and 28th in SIERA on the season. Stringing together quality innings and slowing down this Cubs offense will be a very challenging task.

On the flip side, the White Sox are in a good spot to produce runs. They are first in the majors in run production since the All-Star break and now draw Ben Brown, who owns a 6.48 ERA through more than 83 innings of work.

Brown has given up at least six runs in three of his last four starts and is likely to have a difficult time slowing down this suddenly hot White Sox offense. Look for both teams to carry their weight in a high-scoring affair.

Caesars QuickPick: Our Cubs vs White Sox same-game parlay (SGP)

Coming soon!

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Cubs vs White Sox odds

Cubs vs White Sox live odds

Cubs vs White Sox opening odds

  • Moneyline: Cubs -204 | White Sox +170
  • Run line: Cubs -1.5 (-115) | White Sox +1.5 (+105)
  • Over/Under: Over 8.5 | Under 8.5

Odds courtesy of Caesars.

Cubs vs White Sox trend

The Over is 6-3-1 spanning the past 10 games between these two clubs. Find more MLB betting trends for Cubs vs. White Sox.

How to watch Cubs vs White Sox and game info

Location Rate Field, Chicago, IL
Date Sunday, 7-27-2025
First pitch 2:10 p.m. ET
TV Marquee, CHSN
Cubs starting pitcher Ben Brown
(4-7, 6.48 ERA)
White Sox starting pitcher Grant Taylor
(0-1, 3.93 ERA)

Cubs vs White Sox latest injuries

Cubs vs White Sox weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Todd Cordell - Covers
Betting Analyst

Todd Cordell is a data-driven betting analyst. He uses numbers to help identify value across a wide variety of sports, with NHL being his specialty. Shot props, in particular, have proven to be a very fruitful market. Todd has served as a betting analyst in the public sphere for many years, most recently with theScore covering the NHL and MLB.

When not writing about sports betting, Todd stays busy analyzing the New Jersey Devils with a fine-tooth comb for InfernalAccess, his Devils-centric blog. Todd attended Sheridan College and graduated in 2014 with a diploma in print journalism.

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