Detroit Lions at San Francisco 49ers (-7, 46.5)
The last time the San Francisco 49ers and the Detroit Lions met, a fantastic game was overshadowed by an aggressive handshake and some chest bumping and yelling on the way to the locker room. And that was just between the head coaches.
Jim Harbaugh and Jim Schwartz are both emotional leaders, and after his team came from behind to knock off a then-unbeaten Lions team on the road in Week 6 last season, Harbaugh was perhaps a little too fired up.
The 49ers get Detroit at home this Sunday night and are favored after topping Green Bay in Week 1. The Lions have lost eight in a row to San Francisco and struggled last Sunday against the St. Louis Rams, needing a last-minute touchdown to overcome three turnovers and earn the win.
TV: 8:20 p.m. ET, NBC.
LINE: 49ers -7, O/U 46.5.
WEATHER: Forecasts are calling for temperatures in the high-50s and sunny skies at Candlestick Park. Winds will be out of the west at 8 mph.
ABOUT THE LIONS (1-0): Matthew Stafford passed for 355 yards but was intercepted three times against St. Louis in the 27-23 victory. His scoring pass to Kevin Smith with 10 seconds left bailed the team out. The bright spot for the offense was Smith, who added a rushing touchdown and piled up 91 yards from scrimmage. Smith could find yards on the ground hard to come by against San Francisco, which held Green Bay to only 45 yards rushing. Detroit was held to 66 yards on 18 carries in the 25-19 loss to the 49ers last season, forcing Stafford to throw 50 passes. Three straight fell incomplete on the key drive, when San Francisco forced a four-and-out with just under two minutes remaining. The Lions have not won at San Francisco since 1975.
ABOUT THE 49ERS (1-0): San Francisco was a candidate for regression after its surprise 13-3 campaign in 2011 but made a strong statement with last Sunday’s 30-22 win at Lambeau Field. Just like last season, the 49ers stopped the run, won the turnover battle and played efficiently on offense, racking up 186 rushing yards on 32 carries. Alex Smith made quick use of his new weapons with a touchdown pass to Randy Moss in the second quarter. Smith only passed for 125 yards at Detroit last season but San Francisco made up for it with 141 yards on 15 carries from Frank Gore and a strong defensive effort. The 49ers allowed the Lions to convert only 2 of 15 third downs in the contest.
* Under is 8-0 in the last eight meetings.
* Lions are 0-4-1 ATS in their last five road games.
* 49ers are 5-0-1 ATS in their last six Week 2 games.
* Lions are 0-3-1 ATS in their last four meetings.
1. San Francisco K David Akers hit three field goals from 40-plus yards last week, including an NFL record-tying 63-yard boot. Akers made nine field goals from 50-plus yards in 2011 - the best mark in the league.
2. Stafford has passed for 350 yards or more in four straight games dating to last season. WR Calvin Johnson (foot) returned to practice Thursday.
3. Moss has 72 catches for 1,182 yards and nine TDs in 13 career games against Detroit.