Saturday’s Premier League slate is headlined by Tottenham Hotspur and Wolves, with a high-flying side hosting a relegation-threatened team at Tottenham Hotspur Stadium.
Spurs have been in great form and given up just three goals, so our Tottenham vs. Wolves predictions are expecting Spurs to keep a clean sheet.
Read on for my free betting picks for Saturday, September 27, with kickoff at 3:00 p.m. ET on USA Network.
Premier League predictions for Tottenham vs Wolves
My Tottenham vs Wolves best bet: Wolves Under 0.5 goals (+115 at Sports Interaction)
We have two teams at very different ends of the Premier League table meeting on Saturday with Spurs, heading into the weekend ranked third, facing bottom-placed Wolves.
Through five games, Wolves are rock-bottom, and the only team in the Premier League who are yet to pick up a single point.
More worrying is that they’ve scored just three goals, the second-lowest total of any team. Those goals have come in just two tilts, with Vitor Pereira’s team having failed to score in three games.
Wolves' lack of firepower is a big issue when they’re facing a Tottenham team who have only given up three goals this season. Only two teams have conceded fewer goals that Spurs, and they’ve kept five clean sheets in seven games across all competitions.
Thomas Frank has got Tottenham well-drilled defensively, and he’s been helped by a back four maintaining their fitness.
The central defensive duo of Micky van de Ven and Cristian Romero have been fantastic and complement each other well, with a potent mix of speed and aggression. They’ve been very strong at home, conceding just one of their goals at Tottenham Hotspur Stadium.
Wolves won't solve this unit on Saturday.
Tottenham vs Wolves same-game parlay (SGP)
Wolves Under 0.5 goals
Tottenham moneyline
Pape Sarr 2+ fouls committed
In addition to our best bet, we’re taking Tottenham to win, as they’ve won three of five games in the Premier League and have lost just one game in all competitions this season. They’ve scored a lot, too, with their 10 goals ranking second amongst all teams in the Premier League.
The final leg of this SGP is for Pape Sarr to commit two or more fouls. The Spurs’ midfielder has committed 10 fouls in four league games this season and is averaging 2.6 fouls per 90 minutes on the field.
Tottenham vs Wolves odds
Tottenham vs Wolves live odds
Tottenham vs Wolves opening odds
- Moneyline: Tottenham -204 | Wolves +525
- Draw: +350
- Over/Under: Over 2.5 | Under 2.5
How to watch Tottenham vs Wolves
| Location | Tottenham Hotspur Stadium, London, England |
| Date | Saturday, September 27, 2025 |
| Time | 9:00 a.m. ET |
| TV | Peacock |
| Weather | 63F, 8 mph winds, 20% PoP. |
 Recent EPL form |
D-W-W-L-W |
 Recent EPL form |
W-L-L-L-W |
Tottenham vs Wolves key injuries
Tottenham: Radu Dragusin CB (Out), Dejan Kulusevski FWR (Out), James Maddison CAM (Out), Dominic Solanke STR (Questionable), Yves Bissouma CM (Questionable).
Wolves: None.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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