We have a FA Cup semifinal battle under the famous Wembley arch between Manchester City and Southampton on Saturday, with a spot in the final at stake.
Man City are deep in a title race in the league, but their quality is clear, which is why our Man City vs. Southampton predictions and free betting picks expect them to win and keep a clean sheet against their Championship opposition.
Man City vs Southampton picks and predictions
My Man City vs Southampton best bet: Man City to win to nil (-110 at Sports Interaction)
Man City is the Premier League’s highest-scoring team, averaging exactly two goals per game against better opposition than Southampton.
Southampton have given up over a goal per game in the Championship, and sit mid-table in shots allowed per game at 12.2.
There’s always a risk of rotation for City, but they have a fairly clean bill of health and should have a strong defense, which is key to the clean sheet.
They’ve got the second-best defensive record in the league, and City have given up an average of under one goal per game, and are giving up just 9.8 shots per game.
Man City vs Southampton same-game parlay (SGP)
Flynn Downes to be shown a card
Faylor Harwood-Bellis 1+ fouls
Man City first-half team total Over 0.5
Flynn Downes has picked up 12 yellow cards this season, and Downes has averaged a staggering card every 0.41 per 90 minutes on the pitch in the Championship, and faces a tough battle against the City midfield.
Former City graduate Taylor Harwood-Bellis will be desperate to impress against his former club. Harwood-Bellis has committed 0.77 fouls per 90 mins played, but will be matched up against Erling Haaland.
Man City are the only team in the Premier League to average over a goal scored per game in the opening 45 minutes of games and will want to get this game wrapped up early in order to rest players ahead of the title run-in.
Man City vs Southampton odds
| Man City | Southampton | |
|---|---|---|
| -435 | Moneyline | +1000 |
| +600 | Draw | +600 |
| Over 3.5 (+100) | Total | Under 3.5 (-147) |
Odds courtesy of Sports Interaction.
How to watch Man City vs Southampton
| Location | Etihad Stadium, Manchester, England |
| Date | Saturday, April 25, 2026 |
| Time | 12:15 p.m. ET |
| TV | ESPN+ |
| Weather | Mostly clear skies with a low chance of rain. |
Man City vs Southampton key injuries
Man City: Josko Gvardiol DEF (Out), Ruben Dias CB (Out), Rodri CM (Questionable).
Southampton: Mads Roerslev RB (Out), Alex McCarthy GK (Out), Jack Stephens CB (Questionable).
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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