It’s that point in the season when the College Football Playoff picture begins to take shape, one matchup at a time.
Both the Oklahoma Sooners and Tennessee Volunteers enter this showdown fighting to keep their playoff hopes alive, each needing every win they can get.
Check out our Oklahoma vs. Tennessee predictions and best bets ahead of kickoff on Saturday, November 1.
Oklahoma vs Tennessee Week 10 predictions
- Oklahoma +2.5 (+102 at FanDuel)
- Under 55.5 (-120 at FanDuel)
- Thomas o22.5 rushing yards (-114 at FanDuel)
- Burks anytime touchdown (+170 at FanDuel)
Oklahoma vs Tennessee best bets
Oklahoma +2.5 (+102 at FanDuel)
A spread of -2.5 matters more and more in college football as coaches better understand when to attempt two-point conversions. With that in mind, and recognizing Josh Heupel is one likely to lean into that understanding, the underdog’s +2.5 holds even more weight.
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Under 55.5 (-120 at FanDuel)
Tennessee has hung points in every SEC game, yes, but three of those opponents were among the SEC’s five-worst defenses — and remember, the Volunteers are another one of those five-worst defenses. Even Georgia’s defense ranks only No. 7 in the SEC.
Against the No. 2 defense in the SEC, Tennessee scored just 20 points, and the game fell short of its total. Oklahoma’s defense is better than Alabama’s, while its offense is notably worse. Expect this to also fall short of its total of 55.5.
Oklahoma vs Tennessee TD pick
Deion Burks anytime touchdown (+170 at FanDuel)
This might end up being my favorite prop of the bunch. We've noted already that the Tennessee offense has a myriad of issues, but on the flip side, it certainly knows how to score.
That game script should lead Oklahoma to chase points at a few junctures in this game and thus force some plays downfield.
Who better to profit from that than Deion Burks?
Burks scored two touchdowns in the opening two games of the season and has not reached paydirt since.
Conveniently, the games in which he scored touchdowns also came in the games in which he had his longest two receptions of the season: 28 yards against Illinois State and 34 yards against Michigan.
When I look at the defense of Tennessee, I see a unit that can be OK from down to down, but where things get messy is slowing explosive plays.
As bad as it has been against the run, it has been worse against the pass, ranking in the bottom 10th percentile in explosive plays allowed.
I have to think Oklahoma sees that and will look to get their most explosive pass catcher involved as much as possible.
Oklahoma vs Tennessee prop pick
Star Thomas Over 22.5 rushing yards (-114 at FanDuel)
This one is interesting because the number seems anchored to Star Thomas's uneven volume in recent weeks rather than his role or efficiency.
On Saturday against Kentucky, he handled ten carries in a blowout and averaged 6.4 yards per rush. The week before at Alabama, he saw only three carries yet produced 8.6 yards per attempt.
The gap in usage does not match the quality of his touches. In this matchup, his efficiency should earn a larger share of the work, which makes this line look short.
Oklahoma's defense is elite, and there is no real debate about that. However, that strength is actually what supports the play.
Tennessee will need to vary looks to generate explosives, and Thomas is the clear home run threat in this backfield.
Thomas hits crease runs with confidence, and turns second-level space into chunk gains.
Against a disciplined unit, the Volunteers should prioritize players who can flip the field in one snap.
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Oklahoma vs Tennessee odds
Oklahoma vs Tennessee game info
| Location: | Neyland Stadium, Knoxville, TN |
| Date: | Saturday, November 1, 2025 |
| Kickoff: | 7:30 p.m. ET |
| TV: | ABC |
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Oklahoma vs Tennessee weather
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