With the Cincinnati Reds entering the weekend as joint leaders of the NL Central and the Detroit Tigers rounding into form, today’s matchup is one of the standouts on the slate, especially after last night’s fireworks.
Nathaniel Lowe mashed a two-run walk-off dinger for Cincinnati yesterday to cap a barrage of homers either side of a rain delay, but my Tigers vs Reds predictions expect the visitors to get revenge here, giving starter Jack Flaherty enough run support to escape with a victory.
Read on for my free MLB picks for this April 25 battle.
Who will win Tigers vs Reds today: Tigers moneyline (-105)
The Detroit Tigers have found a nice rhythm since getting swept in Minnesota earlier this month, and that uptick in form has translated to a 10-4 mark in their last 14 games.
Meanwhile, the Cincinnati Reds have had erratic outings from tonight’s starter Brady Singer, who enters with a 5.32 ERA and could be vulnerable against a potent Detroit lineup.
Jack Flaherty racked up walks in Boston on Monday, but he’s only allowed two earned runs across his last 15 innings of work, so I’m riding with the Tigers, who’ve won six of the past nine meetings between these teams.
COVERS INTEL: At 17-9, the Reds have found ways to grind out wins, but a league-worst .210 batting average is a cause for concern against a veteran like Flaherty.
Tigers vs Reds Over/Under pick: Over 9.5 (+100)
These squads crushed eight homers last night, so look for the scoreboard to be busy again here. The Over is 5-1 in the Tigers’ last six games – and it has cashed easily in their past four matchups against the Reds.
The visitors rank 10th in the majors in hits, and they’ve scored 34 runs across their past six contests. Cincinnati is trending up at the plate too, with 6+ runs in four of its last five outings.
With both starting pitchers searching for their best stuff, we should see the batters on top after the lineups combined for 17 runs and 22 hits last night.
- ML/RL bets: 1-3, -2.36
- Over/Under bets: 3-1, +1.53
Tigers vs Reds odds
- Moneyline: Detroit -107 | Cincinnati -103
- Run line: Detroit -1.5 (+146) | Cincinnati +1.5 (-161)
- Over/Under: Over 9.5 (+105) | Under 9.5 (-161)
Tigers vs Reds trend
The Tigers have won seven of their past 10 matchups against the Reds in Cincinnati. Find more MLB betting trends for Tigers vs. Reds.
How to watch Tigers vs Reds and game info
| Location | Great American Ball Park, Cincinnati, OH |
| Date | Saturday, April 25, 2026 |
| First pitch | 7:15 p.m. ET |
| TV | FOX |
| Tigers starting pitcher | Jack Flaherty (0-1, 3.47 ERA) |
| Reds starting pitcher | Brady Singer (1-1, 5.32 ERA) |
Tigers vs Reds latest injuries
Tigers vs Reds weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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