The Boston Red Sox got thumped in their series opener Friday against the Orioles, stretching their losing streak to four games.
The Orioles look to make it two series wins in a row, and they’re slight home favorites for this Saturday matinee.
My Red Sox vs. Orioles prediction and free MLB picks has the home team extending the Red Sox’s misery for another game on April 25.
Who will win Red Sox vs Orioles today: Orioles moneyline (-104)
The Baltimore Orioles have ripped off wins in three of its last four, and it’s the offense that’s been pulling the strings.
In each of the O’s last three wins, they’ve scored at least seven runs, including a 10-3 pounding of the Boston Red Sox on Friday, going yard six times.
The hot bats get Boston’s struggling lefty Garrett Crochet, who has last two straight starts, giving up 16 hits, four home runs and 15 earned runs in 6+ innings of work.
Baltimore’s Trevor Rogers is struggling himself, but he did own Boston in two starts last year, surrendering just one earned run and striking out 12 in 13.1 innings of work.
COVERS INTEL: Adley Rutschman has been on fire after just returning from the injured list, going 5-for-9 with three HR and eight RBI. He’s in great shape to improve his 1-for-6 line against Crochet.
Red Sox vs Orioles Over/Under pick: Over 8.0 runs (-105)
Friday’s 10-3 Baltimore win broke the streak of five straight Unders in this head-to-head.
But this trend might just continue, considering how much both pitchers have gotten touched up in recent starts.
Rogers has been tagged in two straight starts, giving up five earned runs in an 8-4 loss to the Guardians, a game after getting tagged for four runs and getting chased in 4 2/3 vs Arizona.
These were two middle-of-the-pack offenses, which is encouraging for the BoSox, one of only five MLB teams yet to crack 100 runs scored on the season.
Baltimore will do more of the heavy lifting, but the Red Sox pushing some runs in will help.
- ML/RL bets: 2-5, -1.08 units
- Over/Under bets: 2-4, -0.12 units
Red Sox vs Orioles odds
- Moneyline: Boston -100 | Baltimore -104
- Run line: Boston -1.5 (+170) | Baltimore +1.5 (-178)
- Over/Under: Over 8.5 (+117) | Under 8.5 (-122)
Red Sox vs Orioles trend
Boston has just three wins in its last 11 games. Find more MLB betting trends for Red Sox vs. Orioles.
How to watch Red Sox vs Orioles and game info
| Location | Oriole Park at Camden Yards, Baltimore, MD |
| Date | Saturday, April 25 2026 |
| First pitch | 4:05 p.m. ET |
| TV | NESN, MASN |
| Red Sox starting pitcher | Garrett Crochet (2-3, 7.88 ERA) |
| Orioles starting pitcher | Trevor Rogers (2-2, 4.06 ERA) |
Red Sox vs Orioles latest injuries
Red Sox vs Orioles weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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