The Toronto Blue Jays continue their series in Houston on Tuesday, sending Trey Yesavage to the mound against Astros right-hander Hayden Wesneski.
After a strong Shane Bieber outing, I’m going back to a pitcher prop, with Yesavage’s knack for working deep leading my card.
Read on for my Blue Jays vs. Astros predictions and MLB picks for this Tuesday, Aug. 4 matchup.
Blue Jays vs Astros predictions
Blue Jays vs Astros best bet: Trey Yesavage Over 17.5 outs (-110)
After Shane Bieber pitched well against the Houston Astros, I’m following up with another pitcher prop. Trey Yesavage hasn’t been consistent with his strikeout totals, but he has a real knack for working deep into games.
He handled Houston back on June 24, allowing just one run over 5 2/3 innings and grinding out 17 outs even while issuing five walks.
He's been much sharper with his command since, which should help him pile up outs again. I wouldn’t play any number higher than 17.5, and I’d go until -120.
COVERS INTEL: Astros hitters are just 2-for-20 lifetime against Trey Yesavage with a .150 SLG and .280 OBP.
Blue Jays vs Astros same-game parlay (SGP)
For the SGP, I’m building around Yesavage and the Jays as a live underdog.
I’ll take the Toronto Blue Jays moneyline at plus money, with Yesavage the steadier arm against a thin Houston rotation piece in Hayden Wesneski.
I’ll pair it with Yesavage Over 5.5 strikeouts and Kazuma Okamoto Over 0.5 hits, leaning on the same bat I like to do damage in the short Houston park.
Blue Jays vs Astros SGP
- Blue Jays moneyline
- Trey Yesavage Over 5.5 strikeouts
- Kazuma Okamoto Over 0.5 hits
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Blue Jays vs Astros home run pick: Kazuma Okamoto (+350)
Those short Crawford Boxes sit just 315 feet away at Daikin Park, and Kazuma Okamoto’s pull-happy profile gives him the best shot on the team to go yard. Okamoto has been hot lately, too, slugging .519 with a homer and three extra-base hits over his last seven games.
I especially like the matchup because Okamoto has seen more sweepers than anyone on the roster. Wesneski throws his sweeping curve 33% of the time, just like Cristian Javier last night, and Okamoto handles that pitch better than any Blue Jay, slugging .400 against it with a +2 run value. I like his home run prop until +325.
- Best bets: 15-12, +2.72 units
- SGPs: 3-25, -3.31 units
- HR picks: 3-25, -3.25 units
Blue Jays vs Astros odds
- Moneyline: Toronto +110 | Houston -130
- Run line: Toronto +1.5 (-180) | Houston -1.5 (+155)
- Over/Under: Over 8.5 | Under 8.5
Blue Jays vs Astros trend
Daikin Park has the second-shallowest left-field fence in the Majors (next to Fenway Park), which plays into Kazuma Okamoto’s pull-side power. Find more MLB betting trends for Blue Jays vs. Astros.
How to watch Blue Jays vs Astros and game info
| Location | Daikin Park, Houston, TX |
| Date | Tuesday, August 4, 2026 |
| First pitch | 8:10 p.m. ET |
| TV | Sportsnet |
| Blue Jays starting pitcher | Trey Yesavage (5-5, 3.73 ERA) |
| Astros starting pitcher | Hayden Wesneski (1-0, 4.76 ERA) |
Blue Jays vs Astros latest injuries
Blue Jays vs Astros weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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