Ohio State Favored, Penn State Public’s Pick to Win CFB National Title

The Nittany Lions have the highest percentage of tickets (10.1%) and the second-highest split of the handle (13.2%), while the Buckeyes are only fourth highest in both categories.

Grant Mitchell - News Editor
Grant Mitchell • News Editor
Sep 23, 2025 • 14:29 ET • 4 min read
Photo By - Imagn Images.

The upcoming week of college football figures to play an influential role in determining the leaders in national championship odds.

Key Takeaways

  • Penn State is first in tickets and second in handle for national championship bets.

  • LSU is second in tickets despite opening at +2,000.

  • Three top-25 matchups this weekend promise to shake up the odds board.

Penn State opened as a +850 underdog to win the College Football Playoff, behind Ohio State, Texas, Georgia, and Oregon.

The Nittany Lions haven’t faced a ranked opponent just yet, but at +600 in national championship odds, they’re nearly even with the Buckeyes. They also have the highest percentage of tickets (10.1) and the second-highest split of the handle (13.2%).

Ho-hum Ohio State is actually down to +550 from its +450 odds at market opening, and it only has 9.2% of tickets and 9.4% of the handle, both of which are the fourth highest.

Three teams are tied for third in championship odds at +700. One of those is Oregon, which will take on Penn State in Happy Valley on Saturday in a matchup that could make a big imapct on the odds board.

The Ducks have remained at +700 since odds were first published, yet they only have 4.3% of tickets and 3.7% of the handle backing them. Those marks rank ninth and eighth, respectively.

The other teams at +700 are Texas and Georgia. The Longhorns opened at +550 and have the highest share of the handle (14.4%) and the third-highest split of tickets (9.4%), while the Bulldogs opened at +600 and have 5.1% of tickets (eighth) and 3.5% of the handle (10th).

Yet to be mentioned is LSU, which ranks second in tickets (9.7%) and third in handle (11.1%) despite opening at +2,000. The Tigers are down to +1,000 ahead of their weekend matchup with Ole Miss.

Alabama has also managed to stabilize its season after a disastrous Week 1 loss to Florida State. The Crimson Tide are only +1,300 after opening at +1,200 and have 6.1% of tickets (sixth) and 6.4% of the handle (fifth).

Week 5 odds, matchups to watch

This has the potential to be the most important weekend of college football action until the postseason. A plethora of matchups between ranked opponents and championship contenders means the odds board will undergo an inevitable evolution before next week.

The first of the priority matchups is between No. 4 LSU and No. 13 Ole Miss, which will take place at 3:30 p.m. on Saturday. BetMGM has Ole Miss as a -1.5 favorite despite being +3,500 in national championship odds, well off LSU's pace.

At 7:30 p.m., No. 6 Oregon will visit No. 3 Penn State as a 3.5-point underdog in a rematch of last year’s Big Ten Championship Game, which the Ducks won 45-37.

No. 5 Georgia will host No. 17 Alabama at 7:30 as a -3 favorite. Alabama beat Georgia in a back-and-forth thriller in Tuscaloosa last year, 41-34, but still has lots to prove after its Week 1 loss to FSU.

No. 21 USC and No. 23 Illinois will also battle in a ranked showdown, albeit the two teams are much lower in national championship futures odds. BetMGM has USC as a -6.5 favorite.

The elephant in the room

One team that hasn’t been mentioned is Clemson, which has plummeted from +2,000 at the time of opening to +10,000 amid a 1-3 start to the year. The Tigers were responsible for 7.3% of tickets and 6.1% of the handle, both the fifth-highest marks.

Fellow ACC schools Miami, Florida State, and Georgia Tech have been the biggest beneficiaries of Clemson's struggles. Their odds movement was as follows:

Miami: +3,500 to +1,500
Florida State: +10,000 to +5,000
Georgia Tech: +12,500 to +10,000 

Notre Dame’s disappointing start to the year also coincided in its odds lengthening from +1,200 to +2,500.

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Grant Mitchell - News Editor
News Editor

Grant jumped into the sports betting industry as soon as he graduated from Virginia Tech in 2021. His fingerprints can be found all over the sports betting ecosystem, including his constant delivery of breaking industry news. He also specializes in finding the best bets for a variety of sports thanks to his analytical approach to sports and sports betting.

Before joining Covers, Grant worked for a variety of reputable publications, led by Forbes.

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