Denver @ San Francisco picks

Bo Nix is expected to take some snaps here for the Denver Broncos along with the rest of the starters. Given that the San Francisco 49ers are probably playing the long game with a veteran-laden group, Denver may only need a few series with Nix at the controls to pull into a big lead, and I’m comfortable laying the points with the Broncos in this spot. This is also a wager on the depth at Payton’s disposal, including a running back room that features J.K. Dobbins and rookie RJ Harvey. Even when Denver turns to its second-stringers, there’s enough talent to sustain drives in the ground game.