Chelsea vs Man United Predictions, Picks & Odds for Saturday’s Premier League Match

Jason Ence - Contributor at Covers.com
Jason Ence • Betting Analyst 13+ years betting experience
Updated: Apr 17, 2026 , 10:00 AM ET • 4 min read

All signs point to Kobbie Mainoo being available for Manchester United, and that's a bad sign on Saturday for Chelsea.

Kobbie Mainoo of Manchester United EPL
Photo By - Reuters Connect. Kobbie Mainoo of Manchester United EPL

Chelsea desperately hopes to avoid letting Champions League football slip away when they host Manchester United on Saturday.

The Blues have taken just five points from their last seven matches, and another defeat to the Red Devils could see them drop seven points adrift of fifth-place Liverpool.

My Chelsea vs. Manchester United predictions and free EPL picks Saturday, April 18 explain why there’s value in betting on that to happen.

Premier League predictions for Chelsea vs Man United

My Chelsea vs Man United best bet: Manchester United moneyline (+200 at Sports Interaction)

All signs point to Kobbie Mainoo being available for Manchester United, which is why I love them at this price.

Chelsea have lost five consecutive matches vs. top-flight opposition, failing to score in the last four. The return of Enzo Fernandez is a boost, but not enough to get a result.

The Red Devils looked listless against Leeds with Manuel Ugarte in midfield, but Mainoo’s return gives them a conduit between defense and attack led by the in-form Bruno Fernandes.

The Blues have lost three straight at Stamford Bridge, and their struggles in front of goal make this price a tremendous value.

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Chelsea vs Man United same-game parlay (SGP)

Manchester United moneyline

Casemiro 1+ shot on target

Both teams to score Yes

I do expect Chelsea to find a goal here. Man United lacks depth at CB coming into this match, with the suspensions of both Harry Maguire and Lisandro Martinez causing selection headaches.

Enzo leads all Chelsea players in chances created from open play, and his playmaking ability will be gladly welcomed back.

Chelsea have allowed the fourth-most set-piece goals of any club in the Premier League, and only Arsenal has more set-piece goals than the 16 scored by Man United. Casemiro has been a key part of that, and is a big reason why he’s got a shot on target in four of his last five matches.

Chelsea vs Man United odds

Chelsea vs Man United live odds

Chelsea vs Man United opening odds

  • Moneyline: Chelsea +130 | Man United +245
  • Draw: +223
  • Over/Under: Over 3.5 (-103) | Under 3.5 (-113)

How to watch Chelsea vs Man United

Location Stamford Bridge, London, England
Date Saturday, April 18, 2026
Time 3:00 p.m. ET
TV Peacock
Weather Cloudy
Chelsea Recent EPL form L-L-W-L-L
Manchester United Recent EPL form L-D-W-L-W

Chelsea vs Man United key injuries

Chelsea: RB Reece James (Out), CV Trevoh Chalobah (Doubtful), CB Levi Colwill (Out).
Man United: CB Harry Maguire (Out), CB Lisandro Martinez (Out), CB Matthijs de Ligt (Out), CM Kobbie Mainoo (Questionable), LB Patrick Dorgu (Doubtful).

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Jason Ence - Covers
Betting Analyst

Jason has been hooked on football since watching Real Madrid and Manchester United in the 2003 Champions League, and has been betting on the sport for nearly 15 years. He has given soccer gambling and fantasy advice for nearly a decade, writing for sites including Rotowire, SB Nation, and The TwinSpires Edge.

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