Bucks vs Cavaliers Prediction, Picks & Odds for Tonight’s NBA Game

Despite the Cavaliers' recent success against the Bucks, Giannis Antetokounmpo is primed to ball out on Monday night in Cleveland.

Zak Hanshew - Betting Analyst at Covers.com
Zak Hanshew • Betting Analyst
Nov 16, 2025 • 22:54 ET • 4 min read

NBA

Match starts: 18 hrs
CLE
57 %
MIL
43 %
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Giannis Antetokounmpo Milwaukee Bucks NBA
Photo By - Imagn Images. Bucks F Giannis Antetokounmpo (34) drives through Charlotte's defense.

Dating back nearly two years, the Cleveland Cavaliers have won six straight games against the Central Division rival Milwaukee Bucks. The visiting Bucks will look to snap that streak when they travel to Cleveland on Monday.

Giannis Antetokounmpo has dominated the Cavs in recent matchups, and my Bucks vs Cavaliers predictions expect more of the same as he duels with a red-hot Donovan Mitchell.

Here are my best free NBA picks for this divisional showdown at Rocket Center on November 17.

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Bucks vs Cavaliers prediction

Bucks vs Cavaliers best bet: Giannis Antetokounmpo Over 49.5 points + rebounds + assists (-114)

Milwaukee Bucks superstar Giannis Antetokounmpo is off to a hot start this season, averaging career highs in points (32.6) and assists (7.1) to go with 11.3 rebounds. The Greek Freak is averaging 51 PRA per game, and he’s eclipsed 50 PRA in seven of 12 games overall, including three of five on the road.

Antetokounmpo has been great against the Cleveland Cavaliers in recent matchups, averaging 38 points, 14.5 rebounds, and 5.3 assists over his last four trips to Cleveland. He’s reached at least 50 PRA in each of those games and at least 60 in two of them.

Giannis went for 40/14/9 when he played at Cleveland on October 26, and he’ll look for another strong performance here.

The Cavaliers defense is below average, surrendering the 13th-most points and the eighth-most rebounds per game.

Bucks vs Cavaliers same-game parlay

Milwaukee and Cleveland are each 3-7 ATS across their last 10 games. The Bucks have covered in three of their last five trips to Cleveland, and four of the last five head-to-head matchups have been decided by five points or less.

Donovan Mitchell has been electric over his last seven games, averaging 42.3 PRA. He’s hit the Over on this line in four straight and six of seven. With Darius Garland out, he should be in line for high usage once again.

Bucks vs Cavaliers SGP

  • Giannis Antetokounmpo Over 49.5 points+rebounds+assists
  • Bucks +6.5
  • Donovan Mitchell Over 38.5 points+rebounds+assists

Our "from downtown" SGP: Kuzma steps up

Kyle Kuzma has started three straight games, but his scoring has been feast or famine with totals of 8, 29, and 1. He should remain with the first unit, and in a high-scoring matchup, I’ll take a chance on the Over for this modest scoring line.

Bucks vs Cavaliers SGP

  • Giannis Antetokounmpo Over 49.5 points+rebounds+assists
  • Bucks +6.5
  • Donovan Mitchell Over 38.5 points+rebounds+assists
  • Kyle Kuzma Over 12.5 points

Bucks vs Cavaliers odds

  • Spread: Bucks +6.5 (-110) | Cavaliers -6.5 (-110)
  • Moneyline: Bucks +220 | Cavaliers -270
  • Over/Under: Over 237 (-110) | Under 237 (-110)

Bucks vs Cavaliers betting trend to know

The Cleveland Cavaliers have hit the Game Total Over in 52 of their last 83 games (+17.90 Units / 20% ROI). Find more NBA betting trends for Bucks vs. Cavaliers.

How to watch Bucks vs Cavaliers

Location Rocket Arena, Cleveland, OH
Date Monday, November 17, 2025
Tip-off 7:00 p.m. ET
TV Peacock

Bucks vs Cavaliers latest injuries

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Zak Hanshew - Covers
Betting Analyst

Zak Hanshew has been covering fantasy sports and sports betting since 2018. In addition to Covers, he has also written for Rotoworld and has spent time at FantasyPros, RotoWire, OwnersBox and Sportsbook Review. In his spare time, he can be found spending time with his wife and four kids, playing his guitar, watching Simpsons re-runs, or getting some shots up on the court.

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