Big Favorites, Bills-Patriots Highlight NFL’s Tough Slate in Week 15

Buffalo is getting a lot of action from the public ahead of a major AFC East showdown.

Brad Senkiw - Contributor at Covers.com
Brad Senkiw • News Editor
Dec 12, 2025 • 16:25 ET • 4 min read
Photo By - Imagn Images.

A big-time Week 15 in the NFL is setting up to be a difficult battle between bettors and sportsbooks. 

Key Takeaways

  • Sportsbooks need big favorites like the Seahawks, Eagles, and 49ers to not cover the spread this week.

  • The Bills are drawing a lot of action from the public in a major AFC East matchup.

  • The Lions and Chargers are popular underdogs.

There are a half-dozen favorites listed by more than a touchdown and another six games set at under a field goal. Ticket and handle splits greatly differ across three major sportsbooks. 

One of the toughest contests to figure out is the game of the week in New England, where the Bills are slight 1.5-point favorites against the red-hot Patriots in a massive divisional matchup. The books need the home team to pull it out.

“Bettors like the Bills as small road favorites against the Patriots in a massive AFC East showdown on Sunday,” BetMGM trading manager Christian Cipollini said. “The Broncos are also receiving support as home underdogs versus the Packers. There are eight games with spreads of 6 or more points in Week 15. A few underdogs covering or winning outright will break up parlays.” 

BetMGM reported the highest handle is on Buffalo at 81%. The split is much closer to even at both DraftKings and theScore Bet. The Bills are the most-bet team by handle and tickets at BetMGM, and theScore Bet reported that the Patriots are getting the fifth-most money, followed by Buffalo at sixth.

Week 15 Games DraftKings Splits BetMGM Splits theScore Bet Splits
Bills-Patriots (+1.5) BUF 51% bets
BUF 55% handle
BUF 55% bets
BUF 81% handle
BUF 54% bets
BUF 53% handle
Browns-Bears (-7.5) CLE 50% bets
CHI 58% handle
CHI 57% bets
CHI 53% handle
CHI 50% bets
CHI 71% handle
Jets-Jaguars (-13.5) JAX 59% bets
JAX 56% handle
NYJ 55% bets
NYJ 66% handle
JAX 73% bets
JAX 82% handle
Cardinals-Texans (-9.5) HOU 64% bets
HOU 75% handle
HOU 63% bets 
HOU 68% handle
HOU 72% bets
HOU 51% handle
Raiders-Eagles (-11.5)  PHI 61% bets
LV 64% handle
PHI 67% bets
PHI 57% handle
PHI 71% bets
PHI 89% handle
Ravens-Bengals (+2.5) CIN 67% bets
BAL 64% handle
CIN 60% bets
BAL 58% handle
CIN 73% bets
CIN 67% handle
Chargers-Chiefs (-5.5) LAC 69% bets
KC 86% handle
LAC 66% bets
LAC 52% handle
LAC 75% bets
LAC 67% handle
Giants-Commanders(+2.5) NYG 66% bets
NYG 72% handle
NYG 75% bets
NYG 88% handle
NYG 61% bets
NYG 72% handle
Colts-Seahawks (-13.5) SEA 62% bets
SEA 80% handle
SEA 73% bets
SEA 89% handle
SEA 72% bets
SEA 90% handle
Packers-Broncos (+2.5) DEN 55% bets
GB 52% handle
DEN 68% bets
DEN 77% handle
DEN 61% bets
DEN 52% handle
Titans-49ers (-12.5) SF 71% bets
SF 75% handle
SF 82% bets
SF 51% handle
SF 84% bets
SF 98% handle
Lions-Rams (-6) DET 63% bets
LAR 64% handle
DET 51% bets
LAR 68% handle
DET 77% bets
DET 60% handle
Panthers-Saints (+2.5) CAR 80% bets
CAR 82% handle
CAR 75% bets
CAR 69% handle
CAR 75% bets
CAR 58% handle
Vikings-Cowboys (-5.5) DAL 76% bets
DAL 87% handle
DAL 69% bets
DAL 67% handle
DAL 68% bets
DAL 69% handle
Dolphins-Steelers (-3) PIT 64% bets
PIT 66% handle
MIA 51% bets
MIA 61% handle
MIA 51% bets
MIA 66% handle

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Heavy favorites

There are as many as four games with double-digit spreads, but of those, only one favorite is among the top five most-bet teams this week at BetMGM. The Seahawks (-13.5) have taken the third-highest ticket percentage and fourth-most handle so far this week ahead of their game against a Colts team that could be starting 44-year-old free-agent signing Phillip Rivers at quarterback. 

The public isn’t banking on Indianapolis, which has lost three consecutive games, figuring it out again with Rivers or Riley Leonard, if healthy. Seattle is getting at least 80% of the money at the three sportsbooks and the vast majority of the bets. theScore Bet reported that the Seahawks are the second most-bet team by money this week. 

The Eagles are also seeing a lot of action as 12.5-point favorites, ranking first among all teams by handle at theScore Bet for Sunday’s showdown in Las Vegas. Surprisingly, the Raiders are seeing the majority of the money at DraftKings, but Philadelphia is the leader at BetMGM and theScore Bet. 

In another huge spread game, the 49ers are expectedly getting most of the money and bets as 12.5-point favorites against the Titans. 

Close spreads

BetMGM customers are putting the most money on teams with much lower spreads. The Broncos at +2.5 against the road-favorite Packers are the second-most bet team by tickets and third by handle. Denver is getting 77% of the money at BetMGM, but DraftKings bettors are leaning toward Green Bay. 

Bettors are all over the Panthers (-2.5) at New Orleans this week, ranking second at BetMGM by handle and getting 69% of the money there. The Dolphins are fifth in handle as 3-point underdogs at Pittsburgh on Monday night. Miami is getting over 60% of the money at BetMGM and theScore Bet, but DraftKings has seen more tickets and more handle on the home team. 

As 6-point underdogs against the Rams, the Lions are taking a lot of bets at all three sportsbooks. The Chargers (+5.5) are a popular team getting points against the Chiefs. Both are among the top three most-bet moneyline underdogs at BetMGM

Totals, props

When it comes to totals, bettors are liking the under 39 in Browns-Bears, over 55 in Lions-Rams, and over 49.5 in Bills-Patriots. 

The most popular player prop at BetMGM so far this week is Buffalo’s Ty Johnson to go under 1.5 receptions. Baltimore quarterback Lamar Jackson (+250) is the most-bet anytime touchdown scorer, while Packers running back Emanuel Wilson (+850) leads the first-touchdown scorer market at BetMGM

Cleveland signal-caller Shedeur Sanders throwing over 0.5 touchdowns leads player props at theScore Bet, while Lions running back Jahmyr Gibbs is the most-bet touchdown scorer.

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Brad Senkiw - Covers
News Editor

Brad has been covering sports betting and iGaming industry news for Covers since 2023. He writes about a wide range of topics, including sportsbook insights, proposed legislation, regulator decision-making, state revenue reports, and online sports betting launches. Brad reported heavily on North Carolina’s legal push for and creation of online sportsbooks, appearing on numerous Tar Heel State radio and TV news shows for his insights.

Before joining Covers, Brad spent over 15 years as a reporter and editor, covering college sports for newspapers and websites while also hosting a radio show for seven years.

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