Arizona has won 4 of their last 5 SU and ATS and have given up an average of 17.2 total points in that span. This team is playing better defense and have tons of momentum especially after that win in overtime to the cowboys. The 49ers already beat the cardinals earlier in the year by 16 but that was with John Skelton at the helm. Revenge and motivation will be on the Cardinals side on this one. Arizona playing at home and the 49ers have locked up the division, are missing their best defensive player and perhaps the biggest stable is that they are playing the Steelers next week. Most of the 49ers games this year have been against sub .500 teams this year so you can bet after that beating they took against the Ravens earlier in the year, Jim Harbaugh is already gameplanning for the steelers next week. The 49ers havn't beat anyone this year and Harbaugh wants to show they are legit contenders. This game means nothing to the 49ers. Huge look-ahead spot for the 49ers the division is locked up, star defensive player is out going against a hot arizona team with momentum , revenge, and homefield advantage on their side.
Arizona +4
Arizona ML
Cash it