Denver Broncos at New York Giants (+4, 54.5)
Chapter III of the Manning Bowl takes center stage on Sunday when Eli Manning and the New York Giants host older brother Peyton and the Denver Broncos. That the game will be played at MetLife Stadium - the venue for this season's Super Bowl - only adds to the hype for the sibling rivalry that has seen Peyton win the previous two matchups when he was a member of the Indianapolis Colts. Denver is coming off a 49-27 dismantling of the reigning Super Bowl champion Baltimore Ravens.
The Broncos were already among the prohibitive favorites to come out of the AFC this season and did little to quell such lofty expectations behind Peyton Manning's record-tying seven-touchdown performance. The Giants, meanwhile, stumbled through a mistake-filled 36-31 loss at Dallas that featured six turnovers, including three interceptions by Eli Manning. Still, he passed for 450 yards and four TDs and had New York in position for the victory until he was picked off with under two minutes to play.
TV: 4:25 p.m. ET, CBS.
LINE: The Giants opened as 5.5-point home dogs and the line has moved to +4. The total is currently 54.5.
WEATHER: Temperatures will be in the low-70s with clear skies.
ABOUT THE BRONCOS (1-0): Denver erased a three-point deficit with a spectacular second-half performance as Peyton Manning threw for five of his seven scoring passes and finished with 462 yards overall. Free-agent signee Wes Welker had nine catches for 67 yards and two TDs in his Broncos debut and athletic tight end Julius Thomas added another electrifying dimension to an already high-powered attack with five receptions for 110 yards and two scores. The run game remains in flux but the defense had four sacks and two interceptions despite the absences of Pro Bowlers Von Miller (suspension) and Champ Bailey (foot).
ABOUT THE GIANTS (0-1): New York has serious concerns about its running game after starter David Wilson lost two fumbles and was benched and backup Da'Rel Scott was injured, necessitating the signing of former Giants back Brandon Jacobs. New York's receiving corps showed it has the requisite firepower to keep up with the Broncos, getting three touchdown receptions from Victor Cruz and five catches and over 100 yards each from Cruz (118), Hakeem Nicks (114) and Rueben Randle (101) despite the slew of turnovers. The Giants could be shorthanded in the defensive backfield after cornerback Prince Amukamara suffered a concussion versus Dallas.
* Broncos are 5-1 ATS in their last six road games.
* Giants are 9-4 ATS in their last 13 games in Week 2.
* Over is 8-3 in the Broncos last 11 road games.
* Under is 6-0 in the Giants last six versus a team with a winning record.
1. The Broncos are riding a 12-game regular-season winning streak, the longest in the NFL.
2. Eli Manning has thrown for 12 TDs and the Giants have averaged 44 points in winning their last three home games.
3. Welker has 20 catches in his last two regular-season games versus New York.