Seattle Seahawks at San Francisco 49ers (-7.5, 37.5)
Week 7 kicks off Thursday night with a big NFC West showdown between the visiting Seattle Seahawks and the San Francisco 49ers.
Seattle is coming off an unlikely 24-23 comeback victory at home over New England in which it scored 14 points over the final 7:21 of the fourth quarter. Rookie Russell Wilson upstaged a 395-yard passing performance from Tom Brady by throwing late touchdown passes to Braylon Edwards and Sidney Rice, the latter coming with 1:18 remaining.
San Francisco is hoping to bounce back from a dismal 26-3 home loss to the New York Giants. The 49ers, who outscored their opponents 79-3 in their previous two games, took the lead against New York before allowing 26 unanswered points. They are in danger of losing consecutive contests for the first time under coach Jim Harbaugh, who guided them to a 13-3 record last season - his first with the team.
TV: 8:20 p.m. ET, NFL Network.
LINE: The 49ers opened as high as 9-point home favorites but have been bet down to -7 with action on the Seahawks. The total has also moved, going from 39.5 to 37.5 points.
WEATHER: The forecast is calling for clear skies in the Bay Area, with temperatures in the mid 60s. Winds are expected to blow WSW at 6 mph.
ABOUT THE SEAHAWKS (4-2 SU, 4-2 ATS): Wilson was the first rookie quarterback in the NFL to overcome a 13-point deficit in the fourth quarter since Tennessee's Vince Young, who accomplished the feat in 2006 against the Giants. Wilson has defeated Brady, Green Bay's Aaron Rodgers and Dallas' Tony Romo already this season. Jon Ryan averaged 60.0 yards on four punts Sunday, becoming just the third punter in history to average at least 60 yards on a minimum of four punts and first since Detroit's Bob Cifers, who had a 61.75 average on Nov. 24, 1946. Running back Marshawn Lynch gained only 41 yards on the ground, his lowest total since running for 24 yards against Cincinnati on Week 8 last season.
ABOUT THE 49ERS (4-2 SU, 4-2 ATS): Quarterback Alex Smith, who also was sacked four times, threw three interceptions in Sunday's loss to the Giants. It was the seventh time in his career and first since Dec. 20, 2009, against Philadelphia that the former No. 1 overall pick was picked off three times. Tackle Joe Staley left Sunday's game in the third quarter with a concussion. New York's Ahmad Bradshaw rushed for 116 yards, becoming the first opponent to eclipse the 100-yard mark in San Francisco in 22 games. He also recorded the first rushing touchdown allowed by the 49ers in 14 contests. After recording seven first downs in the opening quarter on Sunday, the 49ers notched a total of seven over the final three periods. Thursday's contest is San Francisco's first divisional game of the season.
* Home team is 5-1 ATS in their last six meetings.
* Seahawks are 2-5 ATS in their last seven meetings in San Francisco.
* Seahawks are 18-37-2 ATS in their last 57 road games.
* 49ers are 21-8-3 ATS in their last 32 home games.
1. 49ers WR Randy Moss became the fourth receiver in NFL history to reach the 15,000-yard mark, joining Jerry Rice (22,895), Terrell Owens (15,934) and Isaac Bruce (15,208). Moss enters Thursday with 15,032 yards.
2. Seattle's top-ranked defense allowed a season-high 475 yards Sunday. None of its first five opponents eclipsed 300 yards.
3. San Francisco K David Akers has kicked a field goal in a franchise-record 22 consecutive games.