t has now been confirmed that Brock Purdy will sit out with a toe injury and San Francisco will turn to Mac Jones. The obvious question for us as bettors is how this changes the picture going into a divisional matchup with the Rams.
San Francisco is not just losing Purdy. Jauan Jennings and Ricky Pearsall are also out, and George Kittle is still on injured reserve. Brandon Aiyuk has not returned, leaving the 49ers with Kendrick Bourne and Demarcus Robinson as the top options at wide receiver. Christian McCaffrey will carry a heavy load both on the ground and as a safety valve in the passing game. On defense, Nick Bosa is gone for the season and the secondary has been patchwork with Malik Mustapha out.
Los Angeles has fewer concerns. Tyler Higbee and Rob Havenstein are both doubtful, but Matthew Stafford is healthy and the Rams have their full set of weapons with Puka Nacua and Davante Adams leading the attack.
The Rams are averaging twenty five points per game while allowing just over twenty. The passing game ranks near the top of the league with more than two hundred sixty yards per game and the run game is producing a respectable one hundred twenty yards on average. The defense has created turnovers and has been able to pressure quarterbacks consistently.
The 49ers are averaging twenty points per game, which is in the bottom third of the league. Their pass offense has been strong in raw yardage at nearly two hundred eighty yards a game but that has not translated to consistent scoring because of red zone inefficiency and a ground game stuck at eighty eight yards per game. The defense has kept them competitive, giving up fewer than nineteen points per game, but losing Bosa changes their ceiling.