Giants 36, Panthers 7: Ramses Barden caught nine passes for 138 yards and Andre Brown ran for 113 yards and two touchdowns as visiting New York scored on eight of its 10 possessions en route to a dominating victory.
Lawrence Tynes kicked a career-high five field goals and Eli Manning completed 27 of 35 passes for 288 yards and a score for the Giants (2-1), who moved the ball at will and built a 20-0 lead after four possessions despite missing a number of key weapons on offense due to injury.
Filling in for Ahmad Bradshaw (neck), Brown had 20 carries and a pair of 1-yard TDs as he nearly doubled his career yardage total of 70. With Hakeem Nicks (foot) and Domenik Hixon (concussion) sidelined, Barden matched his receptions total of last season while coming within 60 yards of his career amount.
Manning connected with tight end Martellus Bennett for a 14-yard touchdown on New York's opening drive and Brown found the end zone for the first time less than three minutes into the second quarter for a 17-0 lead. After Tynes booted his first four field goals, including ones from 47 and 49 yards out, Brown scored with 9:40 remaining in the fourth to make it 33-7.
Cam Newton went 16 of 30 for 242 yards with three interceptions and ran for the only touchdown of the game for the Panthers (1-2), who committed four turnovers and gained only 61 yards on the ground.
GAME NOTEBOOK: New York LB Michael Boley had one of his team's three interceptions, giving him one pick in each of his first three games. ... The Panthers have allowed their opponent to score a touchdown on its opening drive in all three games this season. ... Giants S Antrel Rolle left the game early in the fourth quarter with a knee laceration after running into a camera near the end zone.