My first play of the year will be on the SF vs Green Bay.
5 Unit Play Take San Francisco 49ers over Green Bay Packers
This is clearly a match-up of strengths and weakness, as the 49ers are great on defense and the Packers are great on offense. The 49ers offense and the Packers defense have question marks. I expect this game to go down to the wire and getting over a field goal is too good to pass up. San Francisco by 1.