AVALANCHE 3, RANGERS 1: Rookie Gabriel Landeskog scored his team-leading 21st goal and defenseman Ryan Wilson had two assists to lead visiting Colorado to its 10th win in the last 12 meetings with New York.
Semyon Varlamov made 41 saves, including several key stops late in the third period to secure his 24th win.
The Rangers failed on all five power-play opportunities and had a season-high 42 shots.
Mats Zuccarello went to the crease and deflected All-Star defenseman Dan Girardi's pass past Varlamov to open the scoring midway into the first period.
Matt Hunwick then danced around several New York defenders and beat All-Star Henrik Lundqvist just over four minutes later in the first to tie it at 1-1.
Landeskog tipped a slap shot between Lundqvist's pads at 9:51 of the second period to put Colorado up 2-1 in what proved to be the game-winner.
Paul Stastny added an empty-netter with 14 seconds left to seal the victory.
Colorado has earned points in five straight games, while New York has lost consecutive contests.
GAME NOTEBOOK: Rangers forward Artem Anisimov (shoulder) didn't play. ... New York captain Ryan Callahan (foot) and defenseman Michael Del Zotto (hip) returned from injuries. ... New York is 20-1-4 when scoring a power play goal; 24-19-3 when they don't. ... Avalanche forward Jamie McGinn has seven goals and three assists in 10 games since he was acquired from the San Jose Sharks at the trade deadline.