Chargers 24, Jaguars 6: Ryan Mathews rushed for 110 yards and a touchdown as visiting San Diego moved above the .500 mark for the first time this season.
Philip Rivers completed 22-of-26 passes for 285 yards and one touchdown for the Chargers (4-3), who recorded 27 first downs and outgained the Jaguars 434-353. Rivers (30,023) joined Dan Fouts as the only quarterbacks in franchise history to reach the 30,000-yard plateau.
Chad Henne was 23-of-36 for 318 yards with one interception for Jacksonville (0-7), which has lost its last three meetings with San Diego by a combined 100-33 score. Mike Brown had five catches for 120 yards while Maurice Jones-Drew gained only 37 yards on nine carries as the Jaguars became the first team since the 1984 Houston Oilers to lose their first seven games by double digits.
San Diego took the opening kickoff and drove 80 yards, with Danny Woodhead capping the 13-play drive - which consumed over half of the first quarter - with a 2-yard run for his first rushing touchdown of the season. Rivers made it 14-0 just 2:24 into the second with a 27-yard scoring pass to Eddie Royal.
Jacksonville held the Chargers to a field goal while kicking two of its own until Mathews put away the game with a 3-yard TD run 52 seconds into the fourth quarter.
GAME NOTEBOOK: Royal's touchdown reception was his career-best sixth of the season. ... San Diego P Mike Scifres was a spectator for three quarters as the Chargers scored four times and had the half run out on their first five possessions. ... Henne eclipsed the 300-yard mark for the 11th time in his career.