Seahawks 58, Cardinals 0: Marshawn Lynch rushed for 128 yards and three touchdowns and Seattle forced eight turnovers to remain undefeated at home with a historically lopsided win.
The margin of victory equaled the fourth-largest in NFL history - three games have been decided by 59 points - and the largest involving either team. Seattle also set a franchise record for points, breaking the old mark from a 56-17 win over Buffalo in 1977, and scored the most points ever against the Cardinals, who twice surrendered 56 in 1953 and 2008.
Richard Sherman and Bobby Wagner each had two interceptions for the Seahawks (8-5), who allowed just 154 total yards and remained in position for one of the NFC's wild-card spots.
The switch back to quarterback John Skelton did not pay off for Arizona (4-9), which has lost nine straight since a 4-0 start. Skelton went 11-of-22 for 74 yards with four interceptions before being lifted for rookie Ryan Lindley.
The Seahawks forced six turnovers in the first half and turned two of them into touchdowns. Sherman returned an interception 19 yards for a score and Malcolm Smith scooped up Patrick Peterson's muffed punt for another touchdown.
GAME NOTEBOOK: Seattle recorded its first shutout since 2009, and the Cardinals were blanked for the first time since 2003. … The Seahawks' previous season high for points came in a 30-20 win over Minnesota in Week 9. … Seattle's Anthony McCoy had three catches for 105 yards, and rookie RB Robert Turbin added 108 rushing yards on 20 carries.