San Francisco 5, Arizona 2

Giants 5, Diamondbacks 2: Matt Cain struck out eight in six innings and delivered a two-run double, and Melky Cabrera stayed hot with three hits and two RBIs as visiting San Francisco ended a nine-game losing streak against Arizona.

Cain lined a 2-1 pitch past first baseman Lyle Overbay with two outs in the sixth inning to give the Giants a 4-1 lead and chase Diamondbacks starter Trevor Cahill.

Cain (2-2) allowed one run on three hits and two walks, and improved to 11-6 lifetime against Arizona. He also singled in the fifth.

Three relievers bridged the gap to Santiago Casilla, who worked around a one-out single in the ninth for his seventh save in eight opportunities.

Cahill, who hit two straight batters with two outs before Cain’s double, yielded four runs and six hits in 5 2/3 innings in suffering his first career loss against San Francisco (3-1).

Cabrera hit a ground-rule double in the fifth to put San Francisco on top 2-1 and doubled in the ninth to drive in Brandon Belt, who led off with a triple, to make it 5-2. Cabrera is 18-for-42 (.429) in his last 10 games and 16-for-37 (.432) lifetime at Chase Field.

The Giants took a 1-0 lead in the first on Belt’s RBI groundout. The Diamondbacks tied it in the third when Willie Bloomquist’s sacrifice fly drove in Aaron Hill, who led off with a triple.

Arizona made it 4-2 in the seventh after pinch hitter Paul Goldschmidt reached on shortstop Brandon Crawford’s throwing error, which allowed Jason Kubel to score.

GAME NOTEBOOK: The Giants are 15-0 when leading or tied after eight innings despite the absence of closer Brian Wilson, who is out for the season after undergoing Tommy John surgery. … Cain has allowed eight runs in his last six starts. … Arizona had outscored San Francisco 56-23 during its winning streak. … The Diamondbacks have struck out a major league-leading 278 times. … The Giants committed two errors, including Crawford’s eighth, and have a major league-leading 37.

• Arizona will play their next game at home against San Francisco. The Diamondbacks have a W/L % of .500 after a win and .389 after a loss.
• San Francisco will play their next game on the road against Arizona. The Giants have a W/L % of .467 after a win and .500 after a loss.