Twins 5, Athletics 4: Justin Morneau doubled in the tying run and Ryan Doumit's sacrifice fly scored the go-ahead run in the eighth as host Minnesota snapped its five-game losing streak.
Kurt Suzuki singled home the go-ahead run for the Athletics in the eighth, but Minnesota rallied for two against Ryan Cook (1-1) in the bottom of the inning.
Cook allowed two earned runs in the eighth - the first runs he has allowed in 24 innings over 22 appearances this season.
Morneau dumped a double into left field to score Joe Mauer with the tying run, and Doumit's sacrifice fly to left scored Josh Willingham one batter later.
A day after blowing a one-run lead in the ninth against Detroit, Twins closer Matt Capps loaded the bases before striking out Jonny Gomes for his 10th save.
Oakland's Josh Reddick hit his team-leading 14th home run, a solo shot in the first inning. Kila Ka'aihue added his third homer for the A's, a solo blast in the second.
Minnesota's Trevor Plouffe hit a solo homer in the fifth, his fifth of the season. Alex Burnett (2-0) pitched two-thirds of an inning for the win.
GAME NOTEBOOK: The A's have lost six straight. … A's LH Travis Blackley allowed one run over five innings in his first start of the season. … Twins LH Scott Diamond posted his fourth quality start in five outings, allowing three runs over 6 1/3 innings. … A's 3B Brandon Inge returned from the DL and went 0-for-2. … Mauer went 2-for-3 to extend his hitting streak to eight games.