Yankees 6, Athletics 3: Mark Teixeira and Nick Swisher each hit two-run homers as New York kicked off a nine-game road trip with its third straight win.
Robinson Cano also went deep and Ivan Nova tossed seven solid innings for the Yankees, who halted their three-game road losing streak.
After Curtis Granderson scored on an error by Oakland center fielder Coco Crisp in the third inning, Teixeira deposited a 2-1 offering from Tyson Ross over the wall in right for his sixth blast of the year and a 3-0 lead.
The Athletics got on the board in the fourth on Josh Reddick's solo shot, but Cano led off the fifth with his sixth homer and Swisher made it 6-1 three batters later with his eighth blast.
Nova (5-2) allowed three runs and six hits while walking one. The right-hander, who struck out four, improved to 3-0 on the road this year.
Boone Logan tossed a perfect eighth and Rafael Soriano worked a scoreless ninth for his fourth save in as many chances.
Ross (2-5) lasted just 4 1/3 frames, surrendering six runs - three earned - and 11 hits.
Kila Ka'aihue also homered for Oakland, which has scored three runs or less in nine of its last 13 contests.
GAME NOTEBOOK: Yankees SS Derek Jeter went 0-for-5 with three strikeouts. The captain remains tied with Paul Waner for 15th on the all-time list with 3,152 hits. ... Ross fell to 1-3 over his last four starts but has allowed three earned runs or less in each outing. ... New York has won seven of 10 against Oakland dating to the start of last season.