Check out our quick-hitting betting notes on all 12 Opening Day games in the MLB.
Boston Red Sox at New York Yankees (-120, 8)
Probable starting pitchers: Jon Lester (BOS), CC Sabathia (NYY)
Derek Jeter, Alex Rodriguez, Mark Teixeira and Curtis Granderson will all be starting the season on the disabled list for New York, leaving veterans like recently acquired Vernon Wells and former Boston star Kevin Youkilis to carry the weight. Yankees ace CC Sabathia owns an 8-9 record with a 4.23 ERA in 22 career starts against Boston. The under is 6-0 in Jon Lester’s last six starts vs. American League East opposition.
Miami Marlins at Washington Nationals (-260, 7)
Probable starting pitchers: Ricky Nolasco (FLA), Stephen Strasburg (WSH)
Giancarlo Stanton, who is 5-for-13 in his career against Stephen Strasburg, is the only player that started on Opening Day last season for Miami expected in Monday’s lineup. The over is 5-0 in Strasburg’s last five starts in the opener of a series and Ricky Nolasco is 11-5 against Washington – the most wins he has against any team.
San Diego Padres at New York Mets (-139, 7.5)
Probable starting pitchers: Edinson Volquez (SD), Jon Niese (NYM)
The Padres were 49-37 in their last 86 games a year ago and hope to build on that improvement. San Diego starts that quest without talented third baseman Chase Headley, who is out a couple more weeks with a fractured left thumb. Edinson Volquez is coming off his best season since 2008, striking out 174 in 182 2/3 innings in his first campaign with San Diego. He is 0-4 lifetime against the Mets with a 6.46 ERA in 23 2/3 innings.
Chicago Cubs at Pittsburgh Pirates (-122, 7.5)
Probable starting pitchers: Jeff Samardzija (CHC), A.J. Burnett (PIT)
The Pirates were 16 games above .500 on Aug. 8 before going 16-46 the rest of the way to complete their 20th consecutive losing season. Pittsburgh's active roster is a combined 11-for-61 (.180) against Jeff Samardzija, but OF Andrew McCutchen has enjoyed limited success, going 3-for-10 against him. Samardzija won both of his starts against the Pirates in 2012, compiling 14 strikeouts and a 1.06 ERA in 17 innings. Chicago is 5-1 in its last six games in Pittsburgh.
Colorado Rockies at Milwaukee Brewers (-141, 7.5)
Probable starting pitchers: Jhoulys Chacin (COL), Yovani Gallardo (MIL)
Yovani Gallardo is 0-4 with a 5.82 ERA against the Rockies in eight career appearances. The Brewers are 0-7 in Gallardo’s last seven starts vs. the Rockies, who have taken the last four matchups with the Brew Crew. Colorado was the only NL team the Brewers failed to beat more than once in 2012.
San Francisco Giants at Los Angeles Dodgers (-156, 6)
Probable starting pitchers: Matt Cain (SF), Clayton Kershaw (LAD)
Clayton Kershaw has been particularly tough on the Giants in his career, owning a 1.37 ERA in 16 starts and posting two of his five shutouts. San Francisco 3B Pablo Sandoval has only had two at-bats since March 16 because of a lingering right elbow injury that could force him to sit out the opener. The under is 5-0-1 in the last six meetings.
Los Angeles Angels at Cincinnati Reds (-109, 7.5)
Probable starting pitchers: Jered Weaver (LAA), Johnny Cueto (CIN)
Jered Weaver has thrived in interleague play with a 12-3 career record in 20 starts with a 2.61 ERA. The Angels will rely on Weaver to lead the rotation again this year after he led the American League last season in several categories, including winning percentage (.800), opponents average (.214), WHIP (1.018) and hits per nine innings (7.0). The Angels are 8-1 in last their nine Opening Day games, including four straight wins.
Detroit Tigers at Minnesota Twins (+176, 7.5)
Probable starting pitchers: Justin Verlander (DET), Vance Worley (MIN)
Vance Worley struggled a bit in the spring, finishing with a 5.73 ERA over 22 innings of work -- striking out 13 and walking only three. Justin Verlander, the 2011 AL MVP, gets the ball for the Tigers in the opener for the sixth straight year. Surprisingly, he has never won in five career Opening Day starts (0-1). The Tigers are 8-0 in Verlander’s last eight starts vs. the Twins. Weather forecasts are projecting chilly temperatures around the freezing mark for this game.
Kansas City Royals at Chicago White Sox (-140, 7.5)
Probable starting pitchers: James Shields (KC), Chris Sale (CWS)
Chris Sale has earned his first career Opening Day start after being selected as an All-Star in 2012. He went 3-3 with an impressive 3.12 ERA in six starts against Kansas City last season. The Royals counter with their newly acquired weapon James Shields. Kansas City took 12 of the 18 games in the series last season and the under is 4-0 in the last four meetings.
Philadelphia Phillies at Atlanta Braves (-122, 7)
Probable starting pitchers: Cole Hamels (PHI), Tim Hudson (ATL)
The Phillies are missing one of their top offensive players to start 2013 as catcher Carlos Ruiz begins a 25-game suspension for using a banned stimulant. Atlanta will also will be without its starting catcher for the first month as Brian McCann continues to recover from off-season shoulder surgery. Philadelphia starter Cole Hamels looks more than ready for Opening Day, dominating in five Grapefruit League starts while going 3-0 and holding opponents to a .172 batting average. But the Phillies are 0-5 in the last five meetings when Hamels faces Tim Hudson.
Seattle Mariners at Oakland Athletics (-106, 6.5)
Probable starting pitchers: Felix Hernandez (SEA), Brett Anderson (OAK)
Brett Anderson has stymied the Mariners often in his brief career, compiling a 7-3 record and 1.76 ERA in 13 career outings. But he takes the hill against a Seattle squad that smashed 58 homers in 33 spring-training games. The Athletics went 12-7 against the Mariners last season and have taken seven consecutive meetings.
St. Louis Cardinals at Arizona Diamondbacks (-106, 8.5)
Probable starting pitchers: Adam Wainwright (STL), Ian Kennedy (ARZ)
Ian Kennedy is 1-3 lifetime against the Cardinals and lost both starts last season. The 28-year-old is tough to beat at home - he was 8-4 at Chase Field in 2012 (one of the losses was to St. Louis) and 19-6 over the past two seasons. St. Louis was 5-1 against Arizona in 2012, including 3-0 at Chase Field. The over is 7-0 in the Cardinals’ last seven games as road underdogs.