PITTSBURGH -- Todd Frazier might want to start thinking about packing a bag for a trip to Minneapolis.
The Cincinnati Reds third baseman added to his case Tuesday night to be selected to next month's All-Star Game at Target Field as he hit his team-leading 16th home run to lead off the ninth inning to give the Cincinnati Reds a 6-5 win over the Pittsburgh Pirates on Tuesday night.
The shot to center field off Pirates closer Jason Grilli (0-2) helped give the Reds their fifth win in the last six games after Cincinnati's bullpen blew a three-run lead.
Frazier leads National League third baseman in homers, extra-base hits (31) and slugging percentage (.524).
"He's very confident now that he can be a major league player," Cincinnati manager Bryan Price said of the four-year veteran. "He has been able to put home runs, RBIs, run production and stolen bases into one package."
After falling behind in the count 2-0 with a pair of sliders, Grilli went to his fastball, and Frazier connected.
"You can't fall behind the first guy you face, especially in a tie ballgame," Grilli said. "That's not going to work out very often."
The Pirates lost their second straight game following a four-game winning streak.
"I know he didn't want to walk me and put a guy on base," Frazier said. "I was looking to get a fastball I could handle and, fortunately, I was able to connect."
First baseman Ike Davis, catcher Russell Martin and second baseman Josh Harrison hit RBI singles in a three-run seventh as the Pirates tied the game at 5-5.
The Reds had increased their lead to 5-2 in the top of the seventh on a two-run single by first baseman Joey Votto.
Right-handed reliever Logan Ondrusek (2-2) gave up Harrison's single in the seventh but pitched 1 1/3 scoreless innings for the win. Closer Aroldis Chapman pitched a scoreless but shaky ninth for the save, getting infielder Clint Barmes to fly out to deep left field with two runners on for the final out.
"It was an interesting game in a lot of ways," Price said. "Both teams had their moments, and we had to have some good things happens to win the game. It would have been nice if it were a little easier on the stomach."
Center fielder Billy Hamilton had three hits and two stolen bases for the Reds, while Votto had two hits and three RBIs. Frazier, second baseman Brandon Phillips and left fielder Ryan Ludwick added two hits piece.
Cincinnati is 6-2 against the Pirates this season and has won eight of its last 11 regular-season games at PNC Park, though it lost to Pittsburgh in the NL wild card game last year.
Harrison had a career-high-tying four hits and two RBIs for the Pirates. Left fielder Starling Marte, Davis and shortstop Jordy Mercer added two hits each.
Center fielder Andrew McCutchen extended his hitting streak to 12 games but came up short of becoming the first Pittsburgh player since Rennie Stennett in 1971 to have multiple hits in nine straight games.
Right fielder Gregory Polanco became the first Pirates' player to have a hit in each of the first seven games of his career since Hall of Famer Roberto Clemente in 1955.
"We got nicked early and battled back, but we've got to find a way to be more efficient and win these type of games," Pittsburgh manager Clint Hurdle said.
Both starters pitched six innings. Cincinnati's Johnny Cueto gave up two runs in six innings while also allowing seven hits and four walks, and Pittsburgh rookie Brandon Cumpton surrendered three runs and eight hits in six innings after winning his previous two starts.
NOTES: Pittsburgh 2B Neil Walker took batting practice for the first time since undergoing an appendectomy June 9. He also fielded ground balls. ... Pirates RHP Gerrit Cole played catch Tuesday and said he felt no ill effects from his 34-pitch bullpen session Sunday as he continues to rehab his fatigued right shoulder ... LHP Francisco Liriano is scheduled to play catch Thursday, which would mark his first time throwing since he strained a left oblique muscle June 10. ... Cincinnati RHP Alfredo Simon (9-3, 2.95 ERA) will start Wednesday night against RHP Edinson Volquez (4-5, 3.89). Simon, who is tied for the National League lead in wins with St. Louis RHP Adam Wainwright, made quality starts in 11 of his 13 outings.