South Florida Bulls at Rutgers Scarlet Knights (-4, 46.5)
South Florida hasn't won at Rutgers since 2005 and will head north without two seniors on defense. Freshman quarterback Mike White (79-of-144 for 942 yards,
three touchdowns, eight interceptions) - the team's fourth starting quarterback of the season - will make his fifth straight start.
The Scarlet Knights will likely be without Leonte Carroo (upper body), who is a touchdown away from tying the school's single-single receiving TD record. The Scarlet Knights are ranked seventh in the country in rushing yards allowed (102.3) but are minus-10 in turnovers.
LINE: Rutgers opened at -7 but have moved down to -4. The total is currently at 46.5.
WEATHER: There is a 12 percent of rain.
* Underdog is 7-1 ATS in their last eight meetings.
* South Florida is 0-6 ATS in the last six meetings.
* Under is 9-1 in Rutgers' last 10 games following a SU loss.
Standford Cardinal at Arizona State Sun Devils (-3, 55)
The Cardinal boast an impressive resume that includes victories over Washington, UCLA, Oregon State, Oregon and Notre Dame, in addition to their earlier win against Arizona State.Stanford ranks 13th in the country in points allowed (19 per game) and has yielded no more than 20 points in any of its last six contests.
The Sun Devils improved to 7-0 at home last week with a convincing 58-21 victory over Arizona, as they led 30-7 at the half and cruised despite the absence of leading rusher Marion Grice (leg). D.J. Foster led the way with 124 rushing yards and two touchdowns, helping Arizona State improve its scoring output for the fourth straight game (20, 30, 38 and 58).
LINE: The Sun Devils opened as 3.5-point home faves and have moved slightly to -3. The total is currently 55.
WEATHER: There is a 10 percent chance of rain with a 10 mph wind blowing across the field.
* Favorite is 5-0-1 ATS in their last six meetings.
* Home team is 3-0-1 ATS in their last four meetings.
* Over is 5-2 in the last seven meetings at Arizona State.
Duke Blue Devils vs Florida State Seminoles (-29.5, 63.5)
The game will be played at Bank of America Stadium, Charlotte, North Carolina.
The No. 20 ranked Blue Devils, who have won eight in a row, were picked to finish last in the Coastal Division and are heavy underdogs Saturday, but have come from behind to win their past four contests.
The Seminoles, who ascended to the No. 1 ranking after Alabama lost at Auburn last weekend, average 53.7 points per game. Quarterback Jameis Winston is a frontrunner for the Heisman Trophy, averaging a touchdown pass every 9.1 pass attempts for a Florida State offense that has scored 50 or more points seven times in 12 games.
LINE: The line opened at Florida State -28.5 and moved up to -29.5. The total opened at 61.5 and has jumped up to 63.5.
WEATHER: There is a 76 percent chance of rain with a 9 mph wind blowing across the field.
* Favorite is 5-0 ATS in their last five meetings.
* Road team is 7-2 ATS in their last nine meetings.
* Blue Devils are 0-5 ATS in their last five meetings.
Louisiana Lafayette at South Alabama (-3, 59)
The UL Lafayette Ragin' Cajuns are ranked 42 on offense, averaging 443.7 yards per game. The Ragin' Cajuns are averaging 220.2 yards rushing and 223.5 yards passing so far this season.
The South Alabama Jaguars are ranked 48 on offense, averaging 431.2 yards per game. The Jaguars are averaging 171.0 yards rushing and 260.2 yards passing so far this season.
LINE: The line has held steady at South Alabama -3. The total has moved up from 58 to 59.
WEATHER: There is a 39 percent chance of rain.
* UL Lafayette is 0-4 ATS in its last four games overall.
* South Alabama is 5-1 ATS in its last six games following a SU win.
* Over is 8-0-1 in UL Lafayette's last nine games following a SU loss.
Ohio State Buckeyes at Michigan State Spartans (+5, 51.5)
Game will be played at Lucas Oil Stadium, Indianapolis, Indiana
Ohio State has won a school-record 24 straight games but needed a failed two-point try in the final seconds last week to escape Michigan with a one-point victory. Braxton Miller and Carlos Hyde have combined to rush for 1,070 yards and 13 touchdowns over the past three games against Illinois, Indiana and Michigan.
The Spartans boast the nation’s top rushing, total and pass efficiency defense and complement it with the fifth-best turnover margin (plus-15) in FBS. They are also second nationally in third-down defense (28.7 percent) and fourth in scoring defense (11.8 points per game).
LINE: The line opened +5.5 and is now +5. The total hasn't moved from 51.5.
* Under is 4-1 in the last five meetings
* Ohio State is 6-2-1 ATS in its last nine meetings.
* Road team is 5-0 ATS in their last five meetings.
Utah State Aggies at Fresno State Bulldogs (-2.5, 60.5)
The Aggies were expected to struggle after losing starting quarterback Chuckie Keeton to a season-ending knee injury, but they rallied behind freshman backup Darell Garretson, senior running back Joey DeMartino (12 touchdowns) and a stellar defense.
Fresno State's offense ranks fourth nationally in scoring at 47.3 points per game, and senior quarterback Derek Carr has thrown 45 touchdowns with only five interceptions.
LINE: The Bulldogs opened as 3-point home faves and are now -2.5. The total is currently 60.5.
WEATHER: There is a 10 percent chance of rain.
* Utah State is 5-2 ATS in its last seven meetings.
* Underdog is 6-1 ATS in their last seven meetings.
* Fresno State is 1-5 ATS in its last six home games.