Tennessee Titans at Seattle Seahawks (-11, 40.5)
The Titans are trying to get running back Chris Johnson (294 yards) untracked after he had just 38 yards on 25 carries over the past two games against the New York Jets and Kansas City Chiefs. Tennessee is 1-1 on the road and is one game behind Indianapolis in the AFC South.
The Seattle Seahawks are nearly invincible at home and seek their 11th consecutive victory at CenturyLink Field when they face the Tennessee Titans on Sunday. NFC West-leading Seattle has won this season’s two home games against San Francisco and Jacksonville by a combined 54 points and thrives while playing in perhaps the top home-field environment in the league.
LINE: The line opened Seattle -13.5 and is now -11. The total is currently 40.5.
WEATHER: Temperatures will be in the mid-50s with wind blowing toward the S endzone at 4 mph.
COVERS POWER RANKINGS: Tennessee (+1.0) - Seattle (-8.0) + home field (-3.0) = Seahawks -12.0
* Underdog is 5-0 ATS in their last five meetings.
* Seahawks are 13-3 ATS vs. a team with a winning record.
* Titans are 2-9-1 ATS vs. a team with a winning record.
Jacksonville Jaguars at Denver Broncos (-26.5, 52)
The Jacksonville Jaguars have won the last three meetings with the Denver Broncos, but that seems like ancient history as the teams prepare for what is expected to be a lopsided contest Sunday in Denver.
Denver has won 16 straight regular-season games after a 51-48 shootout at Dallas last week. Peyton Manning (1,884 passing yards, 20 TDs) has the offense moving at a record clip, having scored 230 points through five games - the most in NFL history.
LINE: The line opened Broncos -27.5 and is now -26.5. The total opened 51.5 and is now up to 52.
WEATHER: Temperatures will be in the mid-60s with partly cloudy skies.
COVERS POWER RANKINGS: Jacksonville (+10.5) - Denver (-9.5) + home field (-3.0) = Broncos -23
* Underdog is 5-1 ATS in their last six meetings.
* Over is 5-1 in the last six meetings in Denver.
* Jaguars are 0-6 ATS in their last six games overall.
New Orleans Saints at New England Patriots (-1, 50.5)
New Orleans is one of three undefeated teams in the NFL after passing a big test at Chicago a week ago. The Saints, who have their own star tight end in Jimmy Graham -- who leads the league with 593 receiving yards and ranks third in the NFL in total offense.
The Pats got back wide receiver Danny Amendola in last week's 13-6 setback but he caught just four passes and looked rusty as New England failed to score a touchdown for the first time since a 16-9 loss to the Jets in 2009.
LINE: The Pats opened -1. The total opened 49.5 and is up to 50.5.
WEATHER: Temperatures will be in the low-60s under clear skies.
COVERS POWER RANKINGS: New Orleans (-6.0) - New England (-5.5) + home field (-3.0) = Patriots -2.5
* Saints are 4-1 ATS in their last five meetings.
* Over is 9-2 in Saints last 11 vs. a team with a winning record.
* Patriots are 28-12-1 ATS in their last 41 games following a S.U. loss.
Arizona Cardinals at San Francisco 49ers (-10.5, 40.5)
With Arizona adding quarterback Carson Palmer to the mix in the offseason, it was expected that the Cardinals' passing game would improve dramatically over years past. That has yet to happen, however. The Cardinals rank 22nd in passing yardage per game and Palmer has struggled to find the open man.
The San Francisco 49ers are back to their dominant selves following back-to-back one-sided losses last month. San Francisco has won seven of the last eight meetings, including a 27-13 decision in their previous encounter Dec. 30.
LINE: The 49ers opened -11 and are now -10.5. The total opened 41.5 and is down to 40.5.
WEATHER: Temperatures will be in the low-60s with clear and sunny skies.
COVERS POWER RANKINGS: Arizona (+3.0) - San Francisco (-4.0) + home field (-3.0) = 49ers -10
* Cardinals are 2-7 ATS in their last nine meetings.
* 49ers are 8-2 ATS in their last 10 games in October.
* Over is 12-4 in 49ers last 16 games overall.
Washington Redskins at Dallas Cowboys (-5, 51.5)
Washington is looking for its first divisional victory and emerged from the dregs of the winless with a 24-14 triumph at Oakland in Week 4. The Redskins surrendered an average of 32.7 points in their first three games but tightened things up in the victory over Oakland, holding the Raiders to 298 yards while forcing three turnovers.
Dallas is tied for first place in the unimpressive NFC East and is staring at two straight divisional opponents with a trip to Philadelphia scheduled for Week 7. The Cowboys proved they could hang with anyone offensively last week, and Tony Romo found a third receiver in Terrance Williams (151 yards, one touchdown) to go along with Dez Bryant and tight end Jason Witten and give the offense another dimension.
LINE: The Cowboys opened -4.5 and have been bet up to -5. The total opened 53 and is down to 51.5.
COVERS POWER RANKINGS: Washington (+2.5) - Dallas (-2.0) + home field (-3.0) = Cowboys -7.5
* Redskins are 13-3 ATS in their last 16 meetings.
* Cowboys are 7-18-1 ATS in their last 26 vs. NFC.
* Over is 20-8 in Cowboys last 28 home games.