Houston Texans at Baltimore Ravens (+1, 45)
Star receiver Andre Johnson suffered a concussion in the game against the Titans but is expected to be cleared to play. Johnson is tied for the NFL lead with 20 receptions and Houston appears to have found a sensational complement in first-round pick DeAndre Hopkins (12 receptions, 183 yards).
Baltimore has a key player ailing in running back Ray Rice, who injured his left hip flexor in the contest against Cleveland and hasn’t participated in practices. “He’s not going to need the practice to play in the game,” Ravens coach John Harbaugh said.
LINE: Houston opened -2.5 and moved to -1.5. Total moved from 44.5 to 45.
COVERS POWER RANKINGS: Houston (-5.0) - Baltimore (-1.0) + home field (-3.0) = Ravens +1
WEATHER: Temperatures mid 70s, partly cloudy, winds NNW 11 mph.
* Road team is 5-2 ATS in their last seven meetings.Road team is 5-2 ATS in their last 7 meetings.
* Texans are 0-4 ATS in their last four road games.
* Ravens are 5-1 ATS in their last six games overall.
New York Giants at Carolina Panthers (+1, 46.5)
New York's 10 turnovers - seven of which have been Eli Manning interceptions - are a major cause for concern and have put the defense in a tough spot. The offense has been effective at moving the ball, mostly through the air, and ranks fifth in the league in total yards, but the ground game has to come along and the Giants need to hang onto the ball.
The Panthers find themselves in an 0-2 hole after losing their first two games by a combined six points, including a 24-23 defeat against Buffalo last week. The Panthers have been balanced on offense but they've been far from explosive, ranking 27th in the league with 280.5 total yards per game.
LINE: Carolina opened -1 and moved to +1. Total moved from 45.5 to 47.
COVERS POWER RANKINGS: New York (-1.0) + Carolina (+3.0) + home field (-3.0) = Panthers +1
WEATHER: Temps mid 70s, 22 percent chance of early showers, winds 5 north 5 mph.
* Giants are 4-1 ATS in their last five meetings.
* Over is 4-1 in the last five meetings.
* Road team is 5-2 ATS in their last seven meetings.
Detroit Lions at Washington Redskins (Pick, 48.5)
Detroit is 2-0 against Washington under coach Jim Schwartz, with both victories coming at home. Calvin Johnson had 101 yards and three touchdowns in a 37-25 triumph over the Redskins in their last meeting on Oct. 31, 2010.
Facing a large deficit, the Redskins have been offensive juggernauts in the fourth quarter, outscoring Philadelphia and Green Bay by a combined 26-0 over the final 15 minutes.
LINE: Open pick bounced between -1 and +1. Total moved from 48 to 49.
COVERS POWER RANKINGS: Detroit (+1.0) - Washington (+2.5) + home field (-3.0) = Redskins -1.5
WEATHER: Temps mid 70s, partly cloudy skies, winds NNW 12 mph.
* Under is 6-1-2 in the last nine meetings.
* Home team is 8-2 ATS in their last 10 meetings.
* Lions are 0-4 ATS in their last four meetings in Washington.
San Diego Chargers at Tennessee Titans (-3, 43.5)
Philip Rivers leads a rejuvenated offense that is averaging more than 30 points per game. The only problem: San Diego has allowed as many points as it has scored, thanks to a defense that has surrendered the most passing yards in the league through two weeks.
The Tennessee Titans' defense has helped compensate for a sluggish offense through the first two games of the season. Titans RB Chris Johnson comes into the week ranked sixth in rushing yards (166) but second in attempts (50), averaging just 3.3 yards per carry.
LINE: Opened Tennessee -1 and moved to -3. Total steady at 43.5.
COVERS POWER RANKINGS: San Diego (+2.0) - Tennessee (+3.0) + home field (-3.0) = Titans -2
WEATHER: Temps mid 70s, clear skies, winds NNE 7 mph.
* Chargers are 8-0 ATS in their last eight meetings.
* Over is 5-1-1 in the last seven meetings.
* Favorite is 5-1 ATS in their last six meetings.
Arizona Cardinals at New Orleans Saints (-9, 49)
Carson Palmer has injected some life into Arizona's passing game, but the ground game hasn't been as effective and running back Rashard Mendenhall (toe) is questionable. Palmer should have tight end Rob Housler back in the lineup after missing the first two games with a sore ankle, and the Cardinals have eased receiver Larry Fitzgerald along in practice in hopes he can play through a hamstring injury.
While the Saints' offense has struggled to find the end zone, coordinator Rob Ryan's revamped defense has limited its first two opponents to 320 yards and 15.5 points per game. The overhauled defense did a solid job against Atlanta in Week 1 but was dominant in a 16-14 win versus Tampa Bay, allowing 273 total yards - the Saints' lowest total since Week 15 of the 2011 season.
LINE: Arizona opened -9.5 and moved to -7. Total moved from 48.5 to 49.
COVERS POWER RANKINGS: Arizona (+3.5) + New Orleans (-3.0) + home field (-3.0) = Saints -9.5
* Over is 4-0 in the last four meetings.
* Home team is 4-0 ATS in their last four meetings.
* Cardinals are 2-5 ATS in their last four meetings.
Tampa Bay Buccaneers at New England Patriots (-8.5, 43.5)
Quarterback Josh Freeman is under siege after consecutive subpar outings - he was only 9-for-22 for 125 yards with one touchdown and one interception against the Saints - to spark speculation that he could lose his starting job to rookie Mike Glennon. The Buccaneers have dangerous weapons in second-year running back Doug Martin (209 yards rushing) and wideout Vincent Jackson (231 yards receiving), and the defense has been stout in allowing an average of 17 points.
With wideout Danny Amendola (groin) and running back Shane Vereen (wrist) set to miss a second straight game and tight end Rob Gronkowski still rehabbing from multiple offseason surgeries, Tom Brady has been forced to lean on Julian Edelman (20 receptions) and untested rookies in the receiving corps. Starting running back Steven Ridley has rushed for only 86 yards in two games while the defense has forced six turnovers to tie for second in the league.
LINE: Open New England -7 and moved to -8.5. Total moved from 45 to 43.5.
COVERS POWER RANKINGS: Tampa Bay (+4.0) + New England (-4.5) + home field (-3.0) = Patriots -11.5
WEATHER: Temps low 70s, 83 percent chance of rain, winds WSW 7 mph.
* Buccaneers are 7-2 ATS in their last nine road games.
* Patriots are 2-5 ATS in their last seven games overall.
* Over is 7-3 in Patriots' last 10 home games.
Green Bay Packers at Cincinnati Bengals (+2.5, 49)
While Aaron Rodgers' Week 2 performance was typical, the Packers got a surprising 132-yard effort on the ground from running back James Starks, who replaced Eddie Lacy after the rookie left the game with a concussion. The Packers were forced to juggle their secondary last week after three DBs suffered hamstring injuries. All are questionable for Sunday.
Cincinnati has won the past two meetings against Green Bay and sacked Rodgers six times in its most recent game (2009) but it will be without veteran defensive end Robert Geathers who joined three Bengal linebackers on injured reserve. While questions still abound on Andy Dalton's deep passing ability, he has thrown for 280 and 282 yards in his first two starts and unveiled a new weapon in athletic rookie tight end Tyler Eifert on Monday.
LINE: Cincinnati opened +1 and moved to +2.5. Total moved from 46.5 to 49.
COVERS POWER RANKINGS: Green Bay (-6.0) - Cincinnati (-1.5) + home field (-3.0) = Bengals +1.5
WEATHER: Temps high 60s, clear skies, winds NNE 6 mph.
* Packers are 1-4 ATS in their last five road games.
* Bengals are 7-1 ATS in their last eight games in Week 3.
* Over is 5-1 in Packers last six games overall.
St. Louis Rams at Dallas Cowboys (-3.5, 47)
St. Louis is attempting to start 2-1 for the first time since 2006. The Rams will look for more consistency out of high-priced free agent signing Jared Cook, who caught seven passes for 141 yards and two touchdowns in Week 1 but managed only one grab last weekend.
The last time the Cowboys faced the Rams, DeMarco Murray rushed for a franchise-record 253 yards on Oct. 23, 2011. However, Murray only managed 25 yards on 12 attempts in last week's loss to the Chiefs, a game in which Dallas was unable to force any turnovers after creating six miscues against the New York Giants in Week 1.
LINE: Dallas steady at -3.5. Total moved from 46.5 to 47.
COVERS POWER RANKINGS: St. Louis (+2.5) + Dallas (-2.5) + home field (-3.0) = Cowboys -3
* Under is 4-1 in the last five meetings.
* Rams are 6-1 ATS in their last seven road games.
* Cowboys are 2-10 ATS in their last 12 home games.
Cleveland Browns at Minnesota Vikings (-6.5, 40.5)
Cleveland was already struggling to produce offense with just 16 points in two games and trading RB Trent Richardson, who recorded 950 rushing yards and 11 rushing touchdowns as a rookie, gives an offense starting a third-string quarterback even fewer options. Brian Hoyer starts in place of Brandon Weeden, who injured his thumb in last week's loss to Baltimore.
Vikings quarterback Christian Ponder, who was 16-of-30 against Chicago, is reportedly on the hot seat and could lose snaps to backup Matt Cassel unless his play improves. Ponder is 88-for-127 passing with five touchdowns and two interceptions in his last four games against AFC opponents.
LINE: Minnesota opened -4 and moved to -6.5. Total moved from 41 to 40.5.
COVERS POWER RANKINGS: Cleveland (+5.0) - Minnesota (+2.5) + home field (-3.0) = Vikings -5.5
* Browns are 0-5 ATS in their last five games overall.
* Vikings are 5-1-1 ATS in their last seven home games.
* Under is 5-1 in Browns last six road games.